Microbiology- Exam 2

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By law, certain _________ diseases must be recorded with the public health authorities in order to maintain proper surveillance at the local, state, national, and international levels.

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1

By law, certain _________ diseases must be recorded with the public health authorities in order to maintain proper surveillance at the local, state, national, and international levels.

reportable

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2

The number of persons afflicted with an infectious disease is the _______ rate.

morbidity

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3

Resident biota are found in/on the ________.

All of the choices are correct.

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4

Long-term or permanent damage to tissues or organs resulting from a specific disease are called _______.

sequelae

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5

The effect of "good" microbes against invading microbes is called _______.

microbial antagonism

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6

The study of the frequency and distribution of a disease in a defined population is _______.

epidemiology

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7

Infections that go unnoticed because there are no symptoms are called _______.

asymptomatic

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8

A _______ is an infection indigenous to animals that can, on occasion, be transmitted to humans.

zoonosis

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9

Someone who inconspicuously harbors a pathogen and spreads it to others is a _______.

carrier

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10

The primary, natural habitat of a pathogen where it continues to exist is called the _______.

reservoir

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11

Infection occurs when _______.

pathogens enter and multiply in body tissues

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12

The minimum amount of microbes in the inoculating dose is the _______.

infectious dose

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13

The total number of deaths in a population due to a disease is the _______ rate.

mortality

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14

An infectious agent already existing on or in the body is called _______.

endogenous

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15

_______ are toxins that are the lipopolysaccharide of the outer membrane of gram-negative cell walls.

Endotoxins

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16

The number of new cases of a disease in a population over a specific period of time compared with the healthy population is the ________.

incidence rate

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17

Once a microbe has entered a host, what process performed by certain white blood cells will attempt to destroy the microbes?

Phagocytosis

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18

Local edema, swollen lymph nodes, fever, soreness, and abscesses are indications of _______.

inflammation

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19

The greatest number of pathogens enter the body through the _______.

respiratory system

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20

The stage of an infectious disease when specific signs and symptoms are seen and the pathogen is at peak activity is the _______.

incubation period

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21

Which protein can be produced by a virus-infected cell, in order to communicate with other cells the need to produce antiviral proteins?

Interferon

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22

Inflammation, fever, phagocytosis, and antimicrobial molecules are considered innate because ________.

they are not antigen-specific; they contribute to host defenses regardless of the source of activation

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23

Components of the first line of defense include all the following except ________.

phagocytic white blood cells

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24

Plasma cells ________.

produce and secrete antibodies

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25

Which white blood cells comprise 20% to 30% of the circulating WBCs and are the cells that function in the body's third line of defense?

Lymphocytes

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26

What structures are found along lymphatic vessels and are heavily clustered in the armpit, groin, and neck?

Lymph nodes

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27

The body region where a ciliary escalator helps to sweep microbes trapped in mucus away from that body site is the ________.

respiratory tract

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28

A person will typically experience the sensation of _______ when fever is starting to occur in the body.

chills

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29

Choose the statement that describes the first stage of phagocytosis.

Phagocytes move in response to chemicals from the site of injury or inflammation

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30

Fever is initiated when a substance in circulation, called a(n) _________, acts on the hypothalamus causing it to reset body temperature to a higher setting.

pyrogen

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31

The term ______ is given to any foreign substance that stimulates a specific immune system response.

antigen

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32

What type of molecules act to draw phagocytes to foreign substances?

PAMPs

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33

The least numerous of all white blood cells that release histamine during inflammation and allergic reactions are ________.

basophils

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34

Choose the statement that best describes the characteristics of lymph.

It is formed by fluid that leaves circulation into the surrounding extracellular spaces

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35

What is the first step in the major events of the inflammation process?

Injury and mast cells releasing chemical mediators

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36

The human microbiome is considered an important component of the first line of defense. Which statement adequately reflects its role as a defensive barrier?

The human microbiota competes with pathogens for space and nutrients limiting their ability to cause infection, and trains the immune system to recognize antigens.

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37

Which of the following lymphoid organs or tissues has the immunological function of filtering pathogens from the blood?

Spleen

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38

Histamine, serotonin, and bradykinin are all ________.

vasoactive mediators

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39

A properly functioning immune system is responsible for ________.

All of the choices are correct.

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40

The most numerous WBCs that have multilobed nuclei and are very phagocytic are ________.

neutrophils

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41

Which gland shrinks in size during adulthood and has hormones that function in maturation of T lymphocytes?

Thymus

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42

Antigens that elicit allergic reactions are called ________.

allergens

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43

An example of artificial active immunity would be ________.

chickenpox vaccine which triggers extended immunity to chickenpox

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44

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Neutralization

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45

Which process involves antibodies cross-linking cells or particles into large aggregates?

Agglutination

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46

The benefit of adaptive immunity is the production of _______ that provide long-lasting protection.

memory cells

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47

The major histocompatibility complex is ________.

a set of genes that code for MHC glycoproteins

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48

Adaptive immunity involves the response of ________.

B and T lymphocytes

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49

Choose the statement that describes the method of Tc cell-mediated killing of a target cell.

Apoptosis

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50

Choose the statement that best describes the primary action of B cells.

B cells divide and differentiate into plasma cells that produce antibody and memory cells.

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51

The most significant cells in graft rejection are ________.

cytotoxic T cells

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52

An example of natural active immunity would be ________.

chickenpox infection followed by lifelong immunity

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53

Helper T cells ________.

activate B cells and other T cells

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54

The progeny cells of a B-cell clone are called ________.

plasma cells

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55

Plasma cells ________.

secrete antibodies

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56

Superantigens are ________.

bacterial toxins that activate T cells at a 100 times greater rate than other antigens

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