AP Bio Vocab 11

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5’ Cap

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19 Terms

1

5’ Cap

A modified form of guanine nucleotide added onto the 5′ end of a pre-mRNA molecule.

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2

Alternative RNA Splicing

A type of eukaryotic gene regulation at the RNA-processing level in which different mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns.

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3

Coding Strand

Nontemplate strand of DNA, which has the same sequence as the mRNA except it has thymine (T) instead of uracil (U).

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4

Codon

A three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code.

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5

Domain

(1) A taxonomic category above the kingdom level. The three domains are Archaea, Bacteria, and Eukarya. (2) A discrete structural and functional region of a protein.

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6

Exon

A sequence within a primary transcript that remains in the RNA after RNA processing; also refers to the region of DNA from which this sequence was transcribed.

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7

Intron

A noncoding, intervening sequence within a primary transcript that is removed from the transcript during RNA processing; also refers to the region of DNA from which this sequence was transcribed.

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8

Messenger RNA

A type of RNA, synthesized using a DNA template, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein. (In eukaryotes, the primary RNA transcript must undergo RNA processing to become mRNA.)

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9

Primary Transcript

An initial RNA transcript from any gene; also called pre-mRNA when transcribed from a protein-coding gene.

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10

RNA Polymerase

An enzyme that links ribonucleotides into a growing RNA chain during transcription, based on complementary binding to nucleotides on a DNA template strand.

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11

RNA Processing

Modification of RNA primary transcripts, including splicing out of introns, joining together of exons, and alteration of the 5′ and 3′ ends.

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12

RNA Splicing

After synthesis of a eukaryotic primary RNA transcript, the removal of portions of the transcript (introns) that will not be included in the mRNA and the joining together of the remaining portions (exons).

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13

Signal Peptide

A sequence of about 20 amino acids at or near the leading (amino) end of a polypeptide that targets it to the endoplasmic reticulum or other organelles in a eukaryotic cell.

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14

Signal-Recognition Particle

A protein-RNA complex that recognizes a signal peptide as it emerges from a ribosome and helps direct the ribosome to the endoplasmic reticulum (ER) by binding to a receptor protein on the ER.

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15

Spliceosome

A large complex made up of proteins and RNA molecules that splices RNA by interacting with the ends of an RNA intron, releasing the intron and joining the two adjacent exons.

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16

Template Strand

The DNA strand that provides the pattern, or template, for ordering, by complementary base pairing, the sequence of nucleotides in an RNA transcript.

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17

Transcription

The synthesis of RNA using a DNA template.

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18

Transcription Factor

A regulatory protein that binds to DNA and affects transcription of specific genes.

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19

Transcription Initiation Complex

The completed assembly of transcription factors and RNA polymerase bound to a promoter.

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