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Intraosseous Abscess

Syndactyly

Craniostynostosis

Fractures-found in osteogenesis imperfecta

Blue sclera-found in osteogenesis imperfecta

Achondroplasia

Osteopetrosis

Osteopetrosis

• curvilinear shapes of the trabeculae mimic alphabet characters

• Found in Fibrous Dysplasia

Fibrous Dysplasia

Haphazard Spicules found in Fibrous Dysplasia

Cafe au lait spots found in McCune-Albright Syndrome- associated with Polyostotic Fibrous Dysplasia

Craniofacial involvement with polyostotic disease -Fibrous Dysplasia

Fibrous Dysplasia of the Proximal femur with Shepherd’s Crook Deformity

Polyostotic Fibrous Dysplasia

Osteitis Deformans - Jigsaw puzzle-like mosaic pattern appearance to lamellar bone

Sclerotic phase- prominent cement lines

Left: normal Right: Paget’s Disease

Osteitis Deformans

Cause of Headaches in Osteitis Deformans

Bowing of weakened Pagetoid Bone

Sclerotic, irregular thickening of both cortical and cancellous bone - found in Osteitis Deformans

Pagetic Tibia- Osteitis Deformans

Myostitis Ossificans-bone formation in muscle

Femoral Head with wedge shaped infarct- Osteonecrosis

Legg-Calve-Perthes Disease

Idiopathic Avascular Necrosis of the hip

Synovial Chondromatosis

Slipped Capital Femoral Epiphysis

Acute Osteomyelitis

Acute Osteomyelitis

Brodie Abscess found in Acute Osteomyelitis

Intraosseous Abscess (Brodie Abscess) found in Acute Osteomyelitis

Acute Osteomyelitis - Long bones showing radiolucencies

Pseudomonas Aeruginosa Osteomyelitis

Shows Green pigment - Pyocyanin

shows a draining sinus tract

Chronic Osteomyelitis

Osteomyelitis- Characteristic Xray: lytic focus of bone destruction surrounded by a zone of sclerosis

Osteoporosis

Arrow = increased risk of fracture

Osteoporotic Vertebral Body-Osteoporosis

Osteoporotic Bone

Fracture

Fracture

Rickets - Showing loss of normal cartilage palisades at costochondral junction

Normal bone matrix

Leg bowing due to poor mineralization - Rickets

Rickets- Epiphyses are open, mottled and overgrown

Adult with Osteomalacia and pseudofractures

Rickets- enlarged mass of uncalcified cartilage at costchondral junction

Rickets- Rachitic Rosary: beadlike prominences at junction of a rib and its cartilage

Rickets- child has Rickets secondary to gluten sensitive enteropathy

Can also see Harris Sulcus groove (the arrow)

Frontal Bossing/squared head is prominent

Arrow shows Milkman Fracture

Aka: Looser Zone

Osteomalacia

Osteomalacia

Von Kassa Stain (calcium) - Osteomalacia

surfaces of the bony trabeculae (black) are covered by a thicker than normal layer of osteoid (pink/purple)

Exaggeration of Osteoid Seams

Arrow on left hand: Subperiosteal bone resorption

Arrow on right hand: Bulbous bulging from Brown Tumors

Hyperparathyroidism

Hyperparathyroidism

histologic changes of  hyperparathyroidism are known as osteitis fibrosa (refers to accelerated bone remodeling)

This can progress to cystica

Diaphysis

Metaphysis

Epiphysis

Osteoid Osteoma

Osteoid Osteoma- Well-circumscribed lesion characterized by radiolucency with mineralized nidus (usually <1 to 1.5 cm)

Osteoid Osteoma

Osteoblastoma

Osteoblastoma - Lucent, expansile mass involving spinous process at C5

Osteosarcoma

Osteosarcoma

Osteosarcoma-

• Arrow: Radiographs show “sunburst” pattern, disruption of the cortex and lifting of periosteum forming “Codman triangle”

Osteosarcoma

Osteosarcoma

Osteosarcoma

Osteochondroma

Osteochondroma

Benign cartilage Cap- Osteochondroma

Chondroma- Histologically comprised of well-circumscribed nodules of hyaline cartilage

Chondroma

Chondroma

Maffucci Syndrome

A: multiple soft tissue masses and calcified thrombi

B: Contrast material filling cavernous hemangiomas of the soft tissues

Chondrosarcoma

Histology of grades 1, 2, 3 chondrosarcoma

Cartilage growing within medullary cavity and                 through the cortex

Chondrosarcoma

Malignant cells producing cartilage

Chondrosarcoma

Chondrosarcoma - “cotton wool" appearance characteristic plain film radiograph finding

“popcorn” appearance on CT

“cotton wool" appearance characteristic plain film radiograph finding - Chondrosarcoma

Chondrosarcoma- Tumor arising from pelvic bone

Chondrosarcoma- Tumor destroying bone

Giant Cell Tumor of bone

Soap Bubble Appearance

Giant Cell Tumor of Bone Histology

Giant Cell Tumor of Bone- Gross Path Image

Ewing Sarcoma

Ewing Sarcoma Histology

Ewing Sarcoma Histology

Ewing Sarcoma

Aneurysmal Bone Cyst

Aneurysmal Bone Cyst

Aneurysmal Bone Cyst

Aneurysmal Bone Cyst

Aneurysmal Bone Cyst

Chordoma

Chordoma

Metastatic Tumor

Metastatic Prostate Carcinoma

Metastatic Breast Carcinoma to vertebral body