Inflammation

________: mild or moderate injury (leads to inflammation or degeneration)

________: reaction of vascularized living tissue to local injury, irritants or agents.

________: severe injury (leads to necrosis)

________ leading to an increase in blood flow.

increased blood flow

vasodilatation and increased blood flow

exudate

irritation of nerve endings by metabolites

pain and tissue damage

Hotness

Redness

Swelling

Pain

Loss of function

1. Fever

2. Leukocytosis

3. C-reactive protein positive

4. Cloudy swelling of parenchymatous organs

1. Vascular changes

2. Cellular events

1. Contain and isolate injury

2. Destroy invading microorganisms and inactive toxins

3. Prepare tissue for healing and repair

Physical agents

Tissue necrosis

Foreign bodies

Chemical agents

Infection (most common cause)

Immunological

Infection

• Acute inflammation

• Chronic inflammation

Reversible

Irreversible

inflammation or degeneration

necrosis

_______ leads to necrosis and is irreversible

_____ leads to inflammation or degeneration and is reversible