Chapter 13: Viruses, Viroids, and Prions

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Viruses

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1

Viruses

________ that infect bacteria are called bacteriophages, or phages.

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2

Multiply

________ inside living cells by using the synthesizing machinery of the cell.

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3

TSTA

After being transformed by viruses, many tumor cells contain a virus- specific antigen on their cell surface, called tumor- specific transplantation antigen (________), and transformed cells tend to be irregularly shaped, compared to normal cells.

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4

Prusiner

________ coined the name prion for proteinaceous infectious particles.

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5

protein coat

Some viroids, called virusoids, are enclosed in a(n) ________.

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6

capsid

Each ________ is composed of protein subunits called capsomeres.

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7

multiplication of viruses

The ________ can be demonstrated with a one- step growth curve.

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8

Plaques

________ are visible against a lawn of bacterial growth on the surface of the agar.

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9

Oncogenes

________ were first identified in cancer- causing viruses and were thought to be a part of the normal viral genome.

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10

plant diseases

Some ________ are caused by viroids, short pieces of naked RNA, only 300 to 400 nucleotides long, with no protein coat.

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11

lytic cycle

The ________ ends with the lysis and death of the host cell, whereas the host cell remains alive in the lysogenic cycle.

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12

viral DNA

The ________ is then inte- grated into a host cell chromosome as a provirus.

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13

persistent viral infection

A(n) ________ (or chronic viral infection) occurs gradually over a long period.

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14

Viruses

________ capable of inducing tumors in animals are called oncogenic viruses, or oncoviruses.

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15

protein coat

Contain a(n) ________ (sometimes itself enclosed by an envelope of lipids, proteins, and carbohydrates) that surrounds the nucleic acid.

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16

Viruses

________ were originally distinguished from other infectious agents because they are especially small (filterable) and because they are obligatory intracellular parasites- that is, they absolutely require living host cells in order to multiply.

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17

Obligatory intracellular parasites

Require living host cells in order to multiply

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18

Host range

spectrum of host cells the virus can infect

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19

bacteriophages

Viruses that infect bacteria

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20

Capsid

The nucleic acid of a virus is protected by a protein coat

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21

Capsomeres

Each capsid is composed of protein subunits

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22

Envelope

consists of some combination of lipids, proteins, and carbohydrates

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