Studied by 0 peopleReception
The first step in cell signaling
Tranduction
The second step in cell signaling
Response
The third step in cell signaling
Ligand
Binds to the receptor OR an environmental stimulus can change the shape. The first messenger in signal transduction.
Ligand, GPCR, RTK
Stuff in reception
CAMP, IP3, DAG, CA2+
Examples of second messengers in transduction.
Messengers, amplification, phosphorylation
What happens in signal transduction
Amplification event
The receptor will activate several effectors which make several second messengers which activate several enzymes.
Changes a protein’s shape
What does adding a phosphate group do to a protein?
Process of phosphorylation
A kinase will transfer a phosphate group from ATP and covalently bind it to a protein at specific serine, theronine, or tyrosine residues.
Intracellular receptors
Lipid soluable hormones, like steroids, bind to receptors in the nucleus and not to membrane-bound receptors.
Note
Flashcard