Biology: Stem Cells and Specialised Cells

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what are stem cells?

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1

what are stem cells?

a type of cell that can differentiate into many different types of cells

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2

what is meant by the term undifferentiated?

they are unspecialised and so are not adapted to any particular function

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3

what problem can the division of stem cells cause if too slow?

tissues not efficiently replaced leading to aging

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4

what problem can the division of stem cells cause if too fast or too much?

can form tumours which can lead to the development of cancer

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5

what is meant by potency?

a stem cell’s ability to differentiate into different cell types

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6

what is meant by totipotent?

stem cells that can differentiate into any type of cell

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7

what is meant by pluripotent?

stem cells that can form any tissue type but not whole organisms

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8

what is meant by multipotent?

stem cells that can only form a range of cells within a certain type of tissue

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9

what is the benefit of being a multicellular organism?

groups of cells working together as one unit can make use of resources more efficiently than single cells

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10

how are blood cells an example of the benefit of being a multicellular organism?

they look very different to other cells as they are adapted to their function, white blood cells can fight off pathogens and at the same time red blood cells can supply oxygen to respiring tissues

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11

why do blood cells need to be produced from stem cells? and where are stem cells located?

they have a short life span of around 120 days so need to be replaced consistently, located in the bone marrow

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12

how long do neutrophils live and how many do stem cells reproduce an hour?

they live about 6 hours and stem cells produce around 1.6 billion per kg per hour

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13

what are the two main sources of animal stem cells?

embryonic stem cells and tissue (adult) stem cells

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14

what potency are the two types of animal stem cells at?

embryonic- totipotent but pluripotent once blastocyst (mass of cells) is formed after a few days

tissue- multipotent

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15

how are the two types of adult stem cells recovered?

embryonic- early stage of embryo development

tissue- bone marrow or umbilical cord

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16

where are stem cells found in plants?

in the meristem tissue which is found where growth is occurring e.g., tips of roots and shoots

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17

what potency are plant stem cells at?

pluripotent

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18

what is the normal function of stem cells in plants?

vascular cambium, growth of plant as the vascular tissue grows as the plant grows, form xylem and phloem cells

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19

what diseases can stem cells help treat?

heart disease, type 1 diabetes, parkinsons, alzheimers, birth defects, spinal injuries

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20

what injury can stem cells treat?

burns- new skin can be grown from stem cells

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21

how are stem cells helpful to drug trials?

new drugs can be tested on cultures of stem cells rather before animals

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22

how are stem cells helpful to developmental biology?

they can be used to study the changes as multicellular organisms grow

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23

what are the main objections to using stem cells for research?

religious and moral belief that life starts at conception and so when the cell is destructed during harvesting it is murder, rights of ownership

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24

what are the issues with using stem cells from umbilical cords?

only multipotent cells which restricts their usefulness

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25

how are erthrocytes specialised?

  1. very small, have large SA to V ratio increased by the biconcave shape means oxygen can easily diffuse across their membranes

  2. flexible due to well developed cytoskeleton, allows them to change shape so they can twist and turn as they travel through very narrow capillaries

  3. most organelles lost at differentiation provides more space for haemoglobin molecules

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26

how are spermatozoa specialised?

  1. many mitochondria to provide lots of ATP for the tail to move and propel the cell

  2. small but long and thin so they can move easily

  3. has an acrosome (special type of lysosome) which releases enzymes to digest outer covering of ovum

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27

how are neutrophils specialised?

  1. flexible shape which can mold to the shape of its target

  2. twice the size of erythrocytes so they can ingest pathogens

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28

how are epithelial cells specialised?

  1. many have cilia which are used to waft substances in one direction

  2. squamous epithelial cells are flattened in shape and form a thin cross-section which shortens the diffusion pathway and is permeable

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29

how are palisade cells specialised?

  1. long and cylindrical, pack together quite closely with little space between them for air to circulate, co2 in the air spaces diffuse into cells

  2. large vacuole so that chloroplasts are positioned near the periphery of the cell reducing diffusion distance for co2

  3. contain many chloroplasts for photosynthesis

  4. contain cytoskeleton threads and motor proteins to move the chloroplasts up or down the leaf depending on light intensity

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30

how are guard cells specialised?

  1. they use light energy to produce ATP in order to actively transport potassium ions from the surrounding epidermal cells into the guard cells, lowering their water potential

  2. when water enters via osmosis they swell causing the stomata to enlarge, they are now open and gaseous exchange can occur so co2 can enter the palisade cells for photosynthesis

  3. oxygen can also diffuse out when stomata are open, when the plant doesnt want anything to diffuse out the guard cells lose water and become flaccid closing the stomata

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31

how are root hair cells specialised?

  1. hair like projection increases surface area for absorption of water and mineral ions from the soil into which it projects

  2. special carrier proteins in the plasma membranes in order to actively transport mineral ions in

  3. produce ATP required for active transport

  4. as the mineral ions actively transport in, it lowers the water potential allowing water to enter via osmosis

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32

how is epidermal tissue specialised?

  1. consists of flattened cells which form a protective covering over leaves, stems and roots

  2. some have walls impregnated with a waxy substance forming a cuticle to prevent water loss from the plant

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33

how is vascular tissue specialised?

  1. xylem vessels carry water and minerals from roots to all parts of the plant

  2. phloem sieve tubes transfer products of photosynthesis from leaves to other parts of the plant that don’t photosynthesise

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34

how is meristematic tissue specialised?

  1. can divide by mitosis and differentiate into other types of cells

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35

how are xylem vessels specialised? (vascular cambium)

  1. lignin is deposited into the meristematic cells cell walls to reinforce and water proof them, this does kill them

  2. the ends of the cell breaks down so that the xylem forms continuous columns with wide lumens to carry water and dissolved minerals

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36

how are phloem sieve tubes specialised? (vascular cambium)

  1. sieve tubes lose most of their organelles and sieve plates develop between them

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37

how are companion cells specialised? (vascular cambium)

  1. companion cells retain their organelles and continue metabolic functions to provide ATP for active loading of sugars into the sieve tubes

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38

how is epithelial tissue specialised?

  1. have short cell cycles so can divide up to 2 or 3 times a day to replace worn or damaged tissue

  2. no blood vessels receive nutrients via diffusion so have a very thin cross section to shorten diffusion pathway

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39

how is connective tissue specialised?

  1. the matrix within the cells separates the living cells within the tissue enabling it to withstand forces such as weight

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40

how are muscle cells specialised?

  1. muscle cells are called fibres that are elongated and contain special organelles called myofilaments which allow the muscle tissue to contract

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