Chapter 3 - Biology and Behaviour

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1

genome

  • the complete set of DNA of any organism, including all of its genes

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comparisons of genomes of various species have revealed that

  1. humans have roughtly 20-21k protein-coding genes

  2. genes are possessed by all living things

  3. genes make up only about 1% of the human genome

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genotype

genetic material an invididual inherits.

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phenotype

the observable expression of the genotype, including both body characteristics and behaviour.

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environment

every aspect of individuals and their surroundings other than genes.

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5 relations are fundamental in the development of every child

  1. parents genotype-childā€™s genotype

  2. childā€™s genotype-childā€™s phenotype

  3. childā€™s environment-childā€™s phenotype

  4. childā€™s phenotype-childā€™s environment

  5. childā€™s environment-childā€™s genotype

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genes

  • the basic unit of heredity in all living things.

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what do genes guarantee?

  • humans will be similar to each other at the species level and at the individual level.

  • differences that contriubte to genetic diversity

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random assortment in chromosomes

  • 23 chromosomes are shuffled randomly, with only chance deciding which pair goes into each new egg or sperm

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crossing over

  • DNA switches from one chromosome to the other, resulting in some of the chromosomes of the parents different than their own

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mutations

  • changes in a section of DNA

  • These mutations are either random errors caused by environmental factors or from inherited disorders.

  • Most are harmful, but some increase disease resistance and allow individuals to adapt to crucial aspects of the environment.

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sex chromosomes

  • the chromosomes (X and Y) are chromosomes that determine an individualā€™s designated sex at birth.

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endophenotypes

Genes that influence unobservable, intermediate aspects of the phenotype that impact behaviour, our brain and nervous systems

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regulator genes

genes that control what genes turn on and off in patterns

this results in large diversity in genetic expression

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15

alleles

2 or more different forms of a trait

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homozygous

2 dominant or 2 recessive alleles inherited

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heterozygous

1 dominant and 1 recessive inherited allele

  • the dominant allele will be expressed

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phenylketonuria (PKU)

  • a disorder related to a defective recessive gene on chromosomes that prevents metabolism of the amino acid phenylalanine.

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Parentā€™s contributions to the childā€™s environment

  • Parentā€™s behaviour towards children is genetically influenced along with the preferences, activities, and resources to which they expose their children.

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Childā€™s Phenotype - Childā€™s Environment

  • Children create their own environments by actively selecting surroundings and experiences that match their interests and personalities.

  • Childrenā€™s ability to shape their own environments has profound effects on intellectual development.

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Childā€™s Environemnt - Childā€™s Genotype

  • Epigenetic mechanisms are mediated by the environment, and can alter the functioning of genes and create stable changes in their expression. These changes can be passed onto children.

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methylation

works like a dimmer switch with methyl molecules blocking transcription in the promotor region of the gene in order to turn off gene activity

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behaviour genetics

  • the science concerned wtih how variation in behaviour and development results from the combination of genetic and environmental factors.

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heritable

genetically transmitted

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2 premises used to differentiate genetic and environmental contributions

  • (1) If genetic factors are important for a given trait/behaviour, people who are genotypically similar should be phenotypically similar.

  • (2) If shared environemntal factors are important, people who were raised together should be more similar than people who were raised apart.

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Quantitative behaviour geneticists useā€¦

  • stats to study naturally occcuring genetic and environmental variation in a population by studying the phenotypes of people who differ in the amount of genomic DNA they share.

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Family study design

  • Quantitative behaviour genetics research is used to determine whether phenotypic traits are correlated with the degree to which people are genetically related.

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Twin-study design

  • This design is used to compare correlations for identical twins with those for same-sex fraternal twins.

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Equal environments assumption

  • Both types of twins shared the same prenatal and postnatal environment (in the terms of family and community), so if the correlation between identical twins on a given trait/behaviour is significantly higher than the correlation between fraternal twins, genetic factors are mainly responsible.

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Adoption study design

  • Researchers examine whether adopted childrenā€™s scores are correlated more highly with those of their biological relatives or with those of their adoptive relatives.

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Heritability

  • a statistical estimate of how much of the measured variance on a phenotypic trait among individuals in a given population is attributable to genetic diferences among those individuals.

  • Some heritable traits are temperament, aspects of personality, cognition, and psychopathology.

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Molecular behaviour geneticists examineā€¦

  • specific DNA sequences to identify mechanisms that link genes and behaviour.

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Genome-wide association studies (GWAS)

  • are used to link multiple DNA segments with particular traits.

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Genome-wide complex trait analysis (GCTA)

  • uses genetic resemblance across large groups of individuals to make it possible to differentiate aspects of genes and environment that are confounded within families.

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cell body

  • contains basic biological material that keeps the neuron functioning

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dendrites

  • neural fibers that recieve input from other cells and conduct it toward the cell body in the form of electrical impulses

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axon

  • neural fibers that conduct electrical signals away from the cell body to connections with other neurons

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synapses

  • junctions between the axon terminal of 1 neuron and the cell body of another neuron.

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glial cells

cells that form a myelin sheath

  • function as a neutral stem and progenitor cells, protecting the brain and potentially aiding in regeneration when injured

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myelin sheat

  • a fatty sheath that increases the speed and efficiency of information transmission

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cerebral cortex

  • 80% of the brain and consists of 4 lobes - the frontal lobe, the parietal lob, the temporal lobe, and the occipital lobe.

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occipital lobe

  • primarily involved in processing visual information.

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temporal lobe

  • associated with speech, language, music, and emotional information.

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parietal lobe

  • associated with spatial processing and sensory info integration.

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frontal lobe

  • associated with working memory and cognitive control.

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association areas

lie between the major sensory and motor areas

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cerebral hemispheres

  • Sensory input from one side of the body goes to the opposite side of the brain.

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corpus callosum

  • dense tract of nerve fibers.

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cerebral lateralization

  • the specialization of the hemispheres of the brain for different modes of processing (ex. right hemispheres for faces, left hemispheres for speech).

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Neurogenesis

  • the proliferation of neurons through cell division

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Myelination

  • the formation of myelin around the axons of neurons that speeds and increases information-processing abilities (white matter)

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synaptogenesis

  • the process by which neurons form synapses with other neurons, resulting in trillions of connections.

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synpatic pruning

  • the normal developmental process through which synpases that are rarely activated are eliminated.

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plasticity

  • the capacity of the brain to be affected by experience.

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during specific periodsā€¦

  • the human brain in especially sensitive to specific external stimuli, and the neural organization that occurs (or does not occur) during these periods is typically irreversible.

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experience-expectant processes

  • The process where normal wiring happens just because of the individual being a member of the species.

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exprience-dependent processes

  • The process through which neural connections are created and reorganized throughout life as a function of an individualā€™s experiences.

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infant feeding

  • Breast milk is naturally free of bacteria, strengthens the infantā€™s immune system, and contains important antibodies.

  • It also has a positive effect on cognitive development, which leads to higher IQ scores.

  • For those in countries with unsafe drinking water and fewer public health resources, breast-feeding is essential in promoting positive health outcomes.

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Food preferences

  • Some food preferences are innate.

  • Infants develop a preference for some tastes after 4 months of age

  • they are influenced by prenatal environment and flavour of breast milk

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neophobia

  • an unwillingness to eat unfamiliar foods.

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Why ar some overweight but not others?

  • Genetic and environmental factors play roles in this.

  • Genetic factors are proven in the findings that (1) adopted childrenā€™s weight is more correlated with biological parents than adoptive parents (2) and identical twins raised apart have more similar weight than fraternal twins.

  • POMC - a genetic deletion - can lead to human obesity.

  • Childhood impulsivity also leads to obesity.

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Environmental factors that contribute to obesity

  • A lack of physical education programs, recess activities, healthy cafeteria lunches.

  • Children spend less time outside and more with screens.

  • Less sleep because children spend more time on screens.

  • Unhealthy food is cheaper and more readily available than healthy food.

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Social treatment of obese children

  • Obese children are more likely to struggle with friendships and are generally poorly treated by peers.

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Undernutrition

  • associated with poverty, limited access to healthcare, warfare, famine, natural disasters.

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Vaccines

  • deliver a weak version of the disease to the to promp the body to produce anitbodies to attack it.

  • Antibodies provide protection against subsequent encounters with disease.

  • Some parents believe vaccines are harmful and refuse to take them or to let their children take them.

    • This creates a risk for children and others in the community.

    • Some vaccines operate on herd immunity, meaning a certain population needs to be vaccinated for it to work, so this behaviour can lead to several deaths.

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