Unit 5

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DNA

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DNA Structure & Replication

53 Terms

1

DNA

deoxyribonucleic acid

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2

what are the monomers of nucleic acids?

nucleotides

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3

what are the 3 parts of a nucleotide?

sugar, phosphate, nitrogen base

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4

what are the 4 nitrogen bases in DNA?

adenine, guanine, cytosine, thymine (ATCG)

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5

what molecules make up the sides of the DNA molecule?

sugar, phosphate, and covalent bonds

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6

what bond does helicase unzip?

hydrogen bonds

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7

what molecules make up the rungs of the ladder?

nitrogen bases

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8

what bond holds the 2 strands of DNA together?

hydrogen bond

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9

what bond attaches the phosphate of one nucleotide to the sugar of another?

covalent bond

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10

why must DNA be replicated?

so their daughter cell has a copy and can inherit traits

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11

what are the steps of dna replication?

unwinding, base pairing, joining

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12

what does polymerase do?

adds complementary bases

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13

what does helicase do?

unwinds DNA

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14

what is it called when DNA makes copies of itself?

replication

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15

where does DNA replication occur?

nucleus

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16

where in the cell do proteins synthesize?

ribosome

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17

RNA

ribonucleic acid

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18

what are the three types of RNA

mRNA, tRNA, rRNA

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19

what is the function of mRNA?

carries info from DNA to ribosome

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20

what is the function of tRNA?

carries amino acids to the ribosome and attaches them to mRNA

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21

what is the function of rRNA?

makes ribosomes

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22

unlike DNA, RNA contains...

uracil instead of thymine

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23

a sequence of 3 nucleotides in tRNA is called...

anticodon

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24

a sequence of 3 nucleotides in mRNA is called...

codon

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25

transcription

making RNA from DNA, which occurs in the nucleus

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26

what are the 3 steps of transcription?

  1. helicase unzips DNA

  2. DNA polymerase performs base pairing to create mRNA strand(s)

  3. finally, mRNA leaves nucleus for ribosome

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27

translation

making amino acids from RNA, which occurs in the ribosome

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28

what is an intron?

sequence of DNA that is not involved in coding for a protein

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29

what is an exon?

a segment of a DNA or RNA molecule containing information coding for a protein or peptide sequence

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30

chromosomal mutations

change in number/structure of chromosome

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31

gene mutations

a change in a single gene

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32

mutagens

an agent that changes the structure/sequence of DNA ex. radioactive substances, x-rays, and certain chemicals

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33

gene mutation (point mutation)

one base is switched out for another

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34

gene mutation (frameshift mutation)

insertion or deletion

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35

chromosomal mutation (deletion)

section removed

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36

chromosomal mutation (duplication)

part is duplicated and added to chromosome

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37

chromosomal mutation (inversion)

a segment is reversed

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38

chromosomal mutation (translocation)

sections between two chromosomes are swapped

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39

why do cells divide?

growth, repair, reproduction

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40

growth

larger organisms have more cells

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41

development

multi cell organisms begin as a single cell

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42

repair

make new cells to heal wounds

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43

cell division

mitosis and cytokinesis

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44

mitosis

PMAT: prophase, metaphase, anaphase, telophase

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45

interphase

G1, S, G2

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46

G1

every period, grows

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47

S

chromatin is duplicated, as well as all cell organelles

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48

G2

makes molecules for division, grows

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49

prophase

DNA condenses, nucleus membrane disappears, centrioles seperate

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50

metaphase

chromosomes line up, connect to spindle fibers

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51

anaphase

centromeres divide, chromatids separate to opposite sides.

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52

telophase

chromosomes reach opposite sides, nuclear membrane forms, cell starts splitting

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53

cytokinesis

cleavage furrow for animal cells & cell plate for plant cells

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