Nematodes midterms

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Clinical disease

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1

Clinical disease

________ is largely restricted to individuals with a high worm load.

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2

Hyperinfection

________- can result in autoinfection.

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3

Piperazine citrate

________- suspected intestinal or biliary obstruction since this drug paralyzes worms to aid expulsion.

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4

Ancylostomiasis

________ or hookworm disease, characterised by iron deficiency anaemia.

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5

Penetration

________ of skin- filariform larvae bores through the skin.

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6

Necator americanus

________- eosinophilia count will peak after 2 months.

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7

NIH

Eggs are Rarely survive when it come to detecting it in stool that why we are using ________ swab.

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8

Ectopic Ascariasis

________- due to migration of worm up into the stomach.

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9

DS

________- the eggs in perianal folds, the larva within the egg it will mature with in 4 to 6 hours very fast.

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10

Pulmonary lesions

________- due to migrating larva.

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11

posterior end

Sexes are separate (dieoecious), male is smaller than female & its ________ is curved ventrally.

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12

Macroscopic

________- Direct detection of worm /s in stool or vomit.

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13

heavy infection

Mebendazole /Albendazole- drug of choice but contraindicated in pregnancy & ________.

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14

Genital primordium

________- prominent, conspicuous L1 Rhabditiform Larva.

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15

non bile

Microscopy- ________ stained eggs.

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16

reddish itchy

Creeping eruption- ________ papule along the path traversed by filariform larvae (larva migrans)

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17

Inhalation of infected dust

________ containing embryonated eggs.

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18

Epigastric pain

________, diarrhoea & vomiting during early phase of infection.

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19

Ascariasis

________ is very common to kids /children.

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20

Serology

________ (Ab detection)- mainly reserved for epidemiological studies.

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21

Autoinfection

________- filariform larva.

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22

Capilaria philipinensis

________ (Pudoc worm found in Ilocos Sur.

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23

large collections of worms

Imaging- ________ in abdomen.

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24

sexual transmission

MOT- additional, inhalation and ________.

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25

Persistence of infection

________- due to autoinfection.

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26

Ancylostome dermatitis

________ or Ground itch- occurs at the site of entry (more common in necator), lasts for 2 to 4 weeks.

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27

Personal protection

________- wearing boots & gloves.

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28

Mode of transmission

________- Ingestion of undercooked or raw fishes or seafoods.

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29

Stool examination

________- microscopy: non bile stained egg, segmented.

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30

Eosinophil count

________ increases because eosinophils are responsible for parasitic infection.

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31

Stool examination

________: egg /larva found in stool.

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32
  • Male

smaller, curved posterior end, has spicule

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33
  • Female

larger, tapering posterior end, no spicule

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34

Penetration of skin

filariform larvae bores through the skin

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35

ASCARIS LUMBRICOIDES (ROUNDWORM) Common name

Giant intestinal roundworm

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36

Ascariasis

infection of A.lumbricoides

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37

Penetration through intestinal ulcer (perforation)

peritonitis

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38

Hypersensitivity reactions to worm Ags (toxic body fluids)

urticaria, edema of face, conjunctivitis, irritation of URT

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39

Ectopic Ascariasis

due to migration of worm up into the stomach

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40

Macroscopic

Direct detection of worm/s in stool or vomit

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41

Blood examination

eosinophilia

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42

Imaging

large collections of worms in abdomen

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43

USG

to diagnose hepatobiliary or pancreatic ascariasis

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44

Serology (Ab detection)

mainly reserved for epidemiological studies

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45

Mebendazole/ Albendazole

drug of choice but contraindicated in pregnancy & heavy infection

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46

Piperazine citrate

suspected intestinal or biliary obstruction since this drug paralyzes worms to aid expulsion

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47

Mass treatments with single dose mebendazole or albendazole for all school-age children every three to four months

serves dual function

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48

Necator americanus (Common name

American murderer)

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49
  • A. lumbricoides

human infection

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50
  • Intermediate host of toxocara canis and cati

humans

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51
  • A. duodenale (Common name

Old World Hookworm)

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52
  • N. americanus (Common name

New World Hookworm)

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53
  • Ancylostoma caninum

Dog infection

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  • Ancylostoma braziliense

Cat infection

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55
  • Oval, thin

shelled , colorless

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56

Gardeners & miners

skin of hands

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57

Note

Ancylostoma duodenale can do vertical transmission that can cause Congenital infection

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58

Ancylostoma duodenale

eosinophilia count will peak after 1 month of infection

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59

Ancylostome dermatitis or Ground itch

occurs at the site of entry (more common in necator), lasts for 2 to 4 weeks

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60

Creeping eruption

reddish itchy papule along the path traversed by filariform larvae (larva migrans)

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61

Lesions in the lungs

bronchitis & bronchopneumonia

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62

Abnormal appetite showing Pica or Geophagy

perverted taste for earth, mud or lime

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63

General appearance

pale plumpy with protuberant abdomen & dry lustreless hair

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Blood examination

anaemia, eosinophilia

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Oral iron replacement

ferrous sulphate 400mg tid

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66

Personal protection

wearing boots & gloves

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67

buccal cavity

shorter

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genital primordium

prominent, conspicuous L1 Rhabditiform Larva

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69

Open Mouth

Feeding stage

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70

Final host

man

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71

Infective stage

filariform larva

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72

Diagnostic stage

Rhabditiform larva, egg

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Skin lesions (2 types)

"larva currens"

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74

At the site of entry

urticarial rash

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75

In the perianal region

linear, erythematous urticarial wheal

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76

Pulmonary lesions

due to migrating larva

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77

Autoinfection

filariform larva

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Hyperinfection

can result in autoinfection

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79

Persistence of infection

due to autoinfection

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80

ELISA

to detect Abs

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81

Potentially life threatening disease

treat even if its asymptomatic

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82
  • Disseminated strongyloidosis

5 to 7 days

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83

Strongyloides fuelleborni

causative agent for swollen belly syndrome

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84

TRICHINELLA SPIRALIS ( common name

TRICHINA WORM or muscle worm

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85

Final host

pigs and other mammals that are carnivores or omnivore in nature, so why men infected if the final host are pigs, it is because we man are considered as accidental host or the dead end host

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86

Diagnostic stage

encysted larvae (we use muscle biopsy instead of stool)

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87

Infective stage

encysted larvae

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88

Trichinelliasis / Trichinosis

clinical features depends on the stage

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89

Stage of intestinal invasion

5-7 days, pain in abdomen, nausea, vomiting, diarrhea

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90

Stage of larval migration

fever, urticarial rash, splinter hemorrhages, periorbital & facial edema

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91

Stage of encystation

asymptomatic in light infections; if heavy na sa myalgia na, weakness in heavy infections

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92

Muscle biopsy

encysted larva

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93

Blood

eosinophilia between 2nd & 4th week

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94

Serology

to detect specific Abs by

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95

Thiabendazole & Mebendazole

adult worms

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96

Avoidance of feeding bits & refuse from slaughter houses & farms to pigs

breaks life cycle

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97

IS

embryonated egg

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98

MOT

additional, inhalation and sexual transmission

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99

FH

man

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100

DS

the eggs in perianal folds, the larva within the egg it will mature with in 4 to 6 hours very fast

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