AP Biology Chapter 6

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Metabolism

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27 Terms

1

Metabolism

the totality of an organism’s chemical reactions

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2

Catabolism

-Spontaneous process

-∆G<0

-Exergonic reaction

-Hydrolysis

-Breaking down larger molecules into smaller ones

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3

Anabolism

-Non-spontaneous process

-∆G>0

-Endergonic process

-Dehydration

-Building up smaller molecules into larger ones

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4

Free Energy (G)

Energy available to do work

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5

∆G

G(final state) - G(initial state)

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6

Energy Types

-Thermal

-Potential

-Kinetic

-Chemical

-Heat (Thermal in transfer)

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7

Metabolic Pathway

begins with a specific molecule and end with product(s)

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8

Law of Thermodynamics

1st- Energy is neither created nor destroyed (only transferred)

2nd- With every energy transfer, some is lost in the form of heat (every energy transfer increases entropy)

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9

Energy may decrease in a system but…

the universe’s total entropy always increases

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10

Entropy

a measure of randomness/disorder

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11

Open Systems

energy and matter can be transferred between systems

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12

Closed(Isolated) Systems

exchanges with organisms cannot occur

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13

Are organisms open or closed systems?

open

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14

ATP drives endergonic reactions by…

phosphorylation

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15

Substrate

what an enzyme binds to

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16

Active Site

region on enzymes where a substrate binds

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17

Induced Fit

enzyme wraps around the substrate

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18

The more Free Energy…

the greater the work capacity/instability

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19

Activation Energy (Eᴀ)

initial energy needed to activate a reaction

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20

Catalyst

lowers the Eᴀ(activation energy) needed for a reaction; speeds up the chemical reaction

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21

Cofactors

nonprotein enzyme assisters

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22

Coenzymes

organic cofactors

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23

Energy Coupling

the use of an exergonic reaction to drive an endergonic one

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24

Thermodynamic

the study of energy transformations

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25

What can affect enzyme activity?

pH and temperature

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26

Competitive Inhibitor

bind directly to the active site; compete with the substrate

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27

Noncompetitive Inhibitor

bind to another part of the enzyme (NOT the active site); makes the enzyme change shape, which makes the active site less effective

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