Topic 1 Cell Biology Review

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Cell theory

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78 Terms

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Cell theory

Theory that states that all organisms are composed of cells, and that all cells come from pre-existing cells

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Coarse focus

Dial used to initially focus a light microscope on a specimen

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Differentiation

The alteration of a cell's morphology and physiology through changes in gene expression

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Emergent property

A property of a system that emerges from the interaction of the elements of the system

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Gene expression

The synthesis of a functional gene product, often protein, but also rRNA, tRNA or snRna

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Growth

An increase in physical size

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Homeostasis

The process in which an organism regulates activities within cells and their bodies to keep conditions stable

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Magnification

Ratio of image size to actual size

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Metabolism

The sum of all chemical reactions that occur within an organism or within a cell

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Objective lens

The part of the microscope that gathers light from the specimen and focuses it to produce a real image

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Paramecium

Genus of single-celled ciliated organisms

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Reductionism

An approach to science that holds that a complex system can be best understood as the sum of its parts, and that variables can be studied in isolation

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Response

In behavioural science, the behaviour that is the consequence of a stimulus

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Scale bar

A means of visually indicating the magnification of an image

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Stargardt's disease

A degenerative eye disease that has been the target of stem cell research

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Stem cell

A relatively undifferentiated cell that can give rise to other types of cells and retains the ability to divide

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System

A level of organisation that emerges due to the interaction of elements

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Tissue

A group of cells with a common function and structure

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Amphipathic

Molecule that has hydrophobic and hydrophilic regions

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20

Cholesterol

A lipid that prevents the membrane from becoming too fluid and also prevents it from crystallising

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Davson-Danielli model

Model of the cell membrane in which the phospholipid bilayer is between two layers of protein

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Electron carriers

Proteins arranged in chains on the membrane to allow the transfer of electrons from one carrier to another

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Fluid mosaic model

A model conceived by S.J Singer and Garth Nicolson in 1972 to describe the observed structural features of biological membranes

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Fluidity

Refers to the viscosity of a lipid bilayer of the membrane that allows it to change shape

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Glycoproteins

Proteins that contain oligosaccharide chains

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Hormone-binding sites

Proteins on the outside of the membrane that allow specific hormones to bind

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Hydrophilic

Molecules that are attracted to water

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Hydrophobic

Molecules that are not attracted to water but are attracted to each other

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Integral proteins

Proteins imbedded in the phospholipid bilayer

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Peripheral proteins

Proteins on the surface of the plasma membrane

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Permeability

The rate of passive diffusion of molecules through the membrane, which depends on the electric charge, size and polarity of the molecule

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Phospholipid bilayer

Two layers of phospholipids arranged so that their hydrophobic tails are projecting inwards while their polar head groups are on the outside surfaces

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Phospholipids

A lipid consisting of a glycerol bound to two fatty acids and a phosphate group

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Singer-Nicholson model

Current model of membrane structure that incorporates a fluid mosaic structure in a discontinuous lipid bilayer

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Transport pumps

Proteins in the plasma membrane that release energy and use it to move substances across the membrane

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Endosymbiotic theory

A theory that some eukaryotic organelles, such as mitochondria and chloroplasts, originated as free-living prokaryotes that invaded primitive eukaryotic cells

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Genetic code

A nearly universal sequence of nucleotides in DNA that determines the specific amino acid sequence in the synthesis of proteins

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Louis Pasteur

French scientist that proved, among other things, that the emergent growth of bacteria in nutrient broths is due to biogenesis, not spontaneous generation

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Spontaneous generation

Old theory that believed on the formation of living organisms from non-living matter

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Sterilisation

Technique used for the elimination of microbiological organisms to achieve a sterile microbial environment

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Anaphase

The stage of mitosis and meiosis in which the chromosomes move to opposite ends of the nuclear spindle

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Binary fission

A type of asexual reproduction common among prokaryotes where one cell divides giving rise to two cells, each having the potential to grow to the size of the original cell

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Cancer

General term for more than 100 diseases that are characterised by uncontrolled, abnormal growth of cells

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Cell plate

A membrane that forms midway between dividing plant cells during cytokinesis and later becomes the cell wall

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Centrioles

A self-replicating cylindrical organelle that is involved in the process of nuclear division

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Centromere

The region joining the two sister chromatids where it becomes attached to the spindle fibres

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Chromosomes

Linear strand of DNA bonded to proteins in the nucleus of eukaryotic cells that carries the genetic information

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Cyclins

A family of closely related proteins that regulate the cell cycle in eukaryotic cells

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Cytokinesis

The division of the cytoplasm and the plasma membrane, following the division of the nucleus, resulting in two cells in mitosis

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Equatorial plate

The figure formed by the chromosomes in the centre of the spindle during mitosis

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Metaphase

Stage in mitosis in which chromosomes be coma arranged at the equatorial plate

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Metastasis

Characteristic of malignant tumours of transferring the disease from one organ to another not directly with it

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Microtubule fibres

Hollow protein tubes seen during the mitosis of animal cells

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Mitosis

The process where a single cell divides into two identical cells, each containing the same number of chromosomes and genetic content as that of the original cell

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Mitotic index

The ratio between the number of cells in mitosis to the total of cells

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Mutagens

Chemical agents that increase the rate of genetic mutation

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Oncogens

A gene that causes normal cells to change into cancerous tumour cells

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Prophase

First stage of mitosis during which the chromosomes become visible as pairs chromatids and the nuclear envelope disappears

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Sister chromatids

Two identical strands of DNA joined by a common centromere

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Spindle fibres

Network of filaments that collectively from a mitotic spindle in mitosis. They are involved in moving the chromosomes during nuclear division

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Supercoiling

Twisting in the opposite direction to the turns of the double helix during the first stage of mitosis

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Telophase

The final stage of mitosis in which the separated chromosomes reach the opposite poles of the dividing cell and the nuclei of the daughter cells form around them

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Tumours

Abnormal proliferation of cells, either benign or malignant

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Active transport

Movement of substances across membranes using energy in the form of ATP

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ATP

(Adenosine triphosphate) energy molecule

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Concentration gradient

A gradient resulting from an unequal distribution of ions across the cell membrane

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Diffusion

Passive movement of particles from a region of higher concentration to a region of lower concentration

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Endocytosis

The process in which the cell takes in materials from the outside by infolding of the membrane to form a vesicle

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Exocytosis

The process in which the cell releases materials to the outside by discharging them as membrane-bounded vesicles that pass trough the cell membrane

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Facilitated diffusion

Diffusion through a membrane that requires a protein

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Hypertonic

A more concentrated solution relative to another fluid

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Hypotonic

A less concentrated solution relative to another fluid

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Osmoregulation

Control of the water balance of a living organism

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Osmosis

Passive movement of water molecules from a region of lower solute concentration to a region of higher solute concentration

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Secretion

When material is released from a cell

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Semi-permeable membrane

Membrane that allows some substances to diffuse through but not others

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Transport pumps

Proteins in the plasma membrane that use ATP to move substances across the membrane

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Vesicles

A bubble-like membranous structure that stores and transports cellular products

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