Chapter 22: Stem Cells and Tissue Renewal

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Epithelial tissues

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29 Terms

1

Epithelial tissues

They are essential for covering body surfaces, lining organs, and forming protective barriers throughout the body.

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2

Stem cells

They are undifferentiated cells with the capacity for self-renewal and the ability to differentiate into multiple cell types.

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3

Basal stem cells

They are located in the basal layer of epithelia and have the potential to give rise to differentiating cells.

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4

Transit-amplifying cells

They are the immediate progeny of basal stem cells and undergo rapid proliferation before differentiating into specific cell types.

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5

Asymmetric cell division

It is a common mechanism by which epithelial stem cells self-renew while generating differentiating progeny.

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6

Fibroblasts

They are a type of connective tissue cell that plays a crucial role in the maintenance, repair, and remodeling of various tissues and organs.

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7

Myofibroblasts

They are a specialized form of fibroblast that exhibit properties of both fibroblasts and smooth muscle cells.

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8

Myoblasts

specialized muscle progenitor cells

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9

Blood vessles

They are part of the circulatory system and play a crucial role in transporting blood throughout the body.

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10

Arteries

They carry oxygenated blood away from the heart to various tissues and organs.

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11

Veins

They return deoxygenated blood back to the heart.

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12

Capillaries

They are tiny, thin-walled vessels that connect arteries and veins. They enable the exchange of nutrients, oxygen, waste products, and hormones between the blood and surrounding tissues.

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13

Tunica intima

It is composed of a single layer of endothelial cells, supported by a thin layer of connective tissue.

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Tunica media

It consists of smooth muscle cells and elastic fibers, which allow the blood vessels to constrict or dilate, regulating blood flow and blood pressure.

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Tunica adventitia

It is a connective tissue layer that provides structural support and contains nerves and blood vessels that supply the blood vessel itself.

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16

Lymphatics

They are a network of vessels that parallel the blood vessels and form the lymphatic system.

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17

Lymphatic vessels

They collect excess interstitial fluid, called lymph, from tissues and transport it back to the bloodstream.

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18

Lymph nodes

They are small structures located along the lymphatic vessels that filter lymph, removing pathogens, cellular debris, and foreign substances.

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19

Lymphocytes

It is a type of white blood cell, reside within the lymphatic system and play a central role in immune responses.

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20

Endothelial cells

They are specialized cells that line the interior surface of blood vessels and lymphatic vessels, forming a thin layer called the endothelium.

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21

Hematopoiesis

It is the process by which new blood cells are formed in the body.

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22

Hematopoietic lineage expansion

Specific progenitor cells are stimulated to undergo increased proliferation and differentiation.

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23

Regeneration

It refers to the ability of an organism to replace lost or damaged tissue with newly formed tissue that restores the original structure and function.

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Repair

It involves the formation of scar tissue to bridge gaps in tissue that cannot be regenerated fully.

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25

Inflammation

It is the initial response to tissue injury, characterized by the recruitment of immune cells, release of cytokines, and activation of various signaling pathways.

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26

Cell proliferation

It occurs as a result of the activation and division of existing cells or the recruitment of stem cells or progenitor cells to the site of injury.

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27

Differentiation

It is the process by which newly generated cells become specialized and acquire the characteristics and functions of the damaged tissue.

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28

Remodeling

It involves the restructuring and maturation of the newly formed tissue, including the organization of cells, deposition of extracellular matrix, and restoration of tissue architecture.

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29

Cell reprogramming

It refers to the process of converting specialized cells into a more flexible state, often resembling embryonic stem cells, which have the ability to give rise to all cell types in the body.

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