Mood/Affect Drugs - PT I DEPRESSION/ANXIETY

increase understanding, correct irrational thinking, improve coping mechanisms, improve insight, reduce vulnerability

diazepam/valium and alprazolam/xanax

p/lam

anxiety

positive modulator to increase inhibitory effect of gaba

cns depression

limbic system and ras

emotional control, behavior and input organization

CNS depression, paradox anxiety, hypotension, tachycardia, resp depression, cancer risk

4, teratogenic

IV can precipitate, smoking decrease effect, disulfiram fluoxetine and cimetidine increase levels

inconsistent, slowly, large

IV flumazenil

fluozetine/prozac

pram, ine

antidepressant

presynaptic neuron, blocks reuptake of serotonin, CNS excitation

long

serotonin syndrome, hyponatremia, increased sodium excretion, insomnia

kidney damage, confusion, fever, agitation, hallucination, incoordination, tremors, hyperreflexes, diaphoresis high bp, usually 24hrs of starting or st johns wort

MAOIs, children under 7

physical dependence and withdrawal, flumazenil, anticholinergic se, cns depression, memory problems no olds, paradox anxiety, teratogenic

suicide, serotonin, weight and sex, anticholingergic, dont stop fast

duloxetine/cymbalta

pram, ine

antidepressant nri

presynaptic, blocks reuptake of serotonin and norepi

blocks dope sorta

serotonin, anorexia, hypertension, insomnia, hyponatremia, tachycardia, tinnitus, vertigo

before

suicide, serotonin, weight and sex, anticholingergic, dont stop fast, cv dysrhythmias

buproprion/wellbutrin

antidepressants butrin

blocks reuptake of serotonin, norepi and dope

increase availability of dope

smoking cessation

suicide, smoking cessation, seizure hx, cv dysrythmias, cns depression

pre, not

ssri, snri, bupropion

benzos