Chromosome Theory of Inheritance
Theory that states Mendelian genes have specific loci on chromosomes, and it is these chromosomes that undergo segregation and assortment
Wild Type
The phenotype for a character most commonly observed in natural populations
Sex-linked Gene
A gene located on either sex chromosome
X-linked gene
Genes found of the human X chromosome
Dúchenme Muscular Dystrophy
A human genetic disease cause by a sex-linked recessive allele and characterized by progressive weakening and loss of muscle tissue
Hemophilia
X-liked recessive disorder defined by the absence of one or more of the proteins required for blood clotting
Barr body
The inactive X in each cell of a female condenses into a compact object is known as this
Linked genes
Genes located near each other on the same chromosome tend to be inherited together in genetic crosses
Genetic Recombination
The production of offspring with new combinations of traits, different from those found in the P generations
Parental Types
Matching one of the true-breeding parental phenotypes
Recombinant Types
A chromosome created when crossing over combines DNA from 2 parents
Crossing Over
The reciprocal exchange of genetic material between non sister chromatids during prophase 1 of meiosis
Genetic Map
An ordered list of the genetic loci along a particular chromosome
Linkage Map
Genetic map based on the recombination frequencies
Map Units
A unit of Measurement of the distance between genes, one map is equivalent to a 1% recombination frequency
Nondisjunction
When a pair of homologous chromosomes fail to move apart properly during meiosis 1, or when sister chromatids fail to separate in meiosis 2
Aneuploidy
The condition when the zygote has an abnormal number of a particular chromosome
Monosomic
Refers to a zygote with a chromosome missing
Trisomic
Refers to a zygote with a chromosome present in triplicate
Polyploidy
Refers to when some organism have more than two complete chromosome sets in all somatic cells
Deletion
When a chromosome fragment is lost
Duplication
When a fragment from a chromosome is duplicated and fused with a homologous chromosome
Inversion
When a fragment reattaches to the original chromosome in the reverse orientation
Translocation
Segment attaches to a non-homologous chromosome
Down Syndrome
Genetic disease caused by the presence of an extra chromosome 21 and resulting in developmental delays, physical differences, and some heart issues
Genomic Imprinting
When variation in the phenotype is dependent upon whether an allele is inherited from the male or female present