blood cells can be classified into three groups:
erythrocytes, leukocytes, and thrombocytes
erythrocytes
red blood cells
leukyocytes
white blood cells
thrombocytes
blood platelets
blast
immature erythrocytes
erythrocytes and leukocytes are formed in the...
bone marrow
hemoglobin
replaces a blast's nucleus as it matures, allows transport of O and CO2
polymorphonuclear
pertaining to nucleus of many forms
polymorphonuclear leukocytes are also called..
granulocytes, because their cytoplasm has granules
granules
tiny particles that contain enzymes for digesting infectious microorganisms
Mononuclear leukocytes are also called...
agranulocytes, because the dont have granules.
agranulocytes are also known as
polymorphonuclear leukocytes
granulocytes are aka
mononuclear leukocytes
types of granulocytes
neutrophils, eosinophils, basophils
neutrophils
destroy pathogens, aka phagocytes
phagocytes
swallow, engulf
eosinophils
secrete stuff that attacks parasites, also respond during an allergic reaction
basophils
contain histamine and heparin, function not fully understood
histamine
is released during an inflammatory response.
heparin
natural acid that prevents coagulation
agranulocytes are classified into..
lymphocytes and monocytes
lymphocytes
involved in immune surveillance, process of detecting and destroying pathogens
monocytes
large, single nucleus phagocytes that swallows dead or dying cells and tissues.
how are macrophages formed?
monocytes turn into macrophages when they move from the bloodstream into body tissues
what happens to monocytes when they move from the bloodstream to the body tissues?
they turn into macrophages
where are macrophages commonly found in?
spleen, liver, and connective tissue
Cell fragments that have broken off megakaryocytes
thrombocytes/blood platelets
megakaryocytes
bone marrow cells with very large nuclei
what do thrombocytes/blood platelets do?
they aid in coagulation
where did thrombocytes/blood platelets come from
they broke off from megakaryocytes
plasma
liquid portion of the blood
plasma contains
water, hormones, protiens, sugar, salts, waste products.
four key proteins in plasma
albumin, globulin, fibrinogen, prothrombin
albumin
maintains proper amount of water. opposes water's tendency to leak into cells and tissues, which would cause edema (swelling)
globulin
makes up large portion of proteins in plasma. three types of it
three types of globulin
alpha, beta, gamma
alpha and beta globulins function
transport lipids thru blood
what helps transport lipids through blood?
alpha and beta globulins
gamma globulins
composed of mainly immunoglobulins, proteins that act as antibodies.
antibodies
proteins that counteracts a specific antigen
fibrinogen
creates bridges between blood platelets, which is involved in blood clotting
fibrinogen and prothrombin are formed in the..
liver
prothrombin
converted into thrombin when injury occurs to blood vessel
the immune system differs from other systems because...
it is not contained within a single set of organs or vessels
how is your integumentary system a part the immune system?
skin is a barrier against pathogens
how is your respiratory system a part of your immune system?
cilia traps pathogens
how is your digestive system a part of your immune system?
stomach acids and enzymes kill pathogens
how is your lymphatic system a part of your immune system?
its network of lymphatic cells, tissues, vessels, and organs plays a central role in fighting pathogens
lymph is also known as...
lymphatic fluid or interstitial fluid
purpose of lymph/lymphatic fluid/interstitial fluid
removes wastes, toxins, and pathogens
lymph, unlike blood...
only has leukocytes and plasma
lymphatic vessels are either...
capillaries or ducts
lymphatic capillaries
thin walled, microscopic tubes that carry lymph to larger vessels. propel in only one way
where do the lymphatic capillaries propel lymph
away from tissues, to thoracic cavity
the right lymphatic duct drains lymph from...
right arm and right side of head and thorax.
the thoracic duct drains lymph from...
lower right and left side of the body
lacteals
specialized lymphatic vessels located in the villi of the small intestine. remove waste products from villi and carries it to the thoracic duct
lymph nodes
filters pathogens from lymph before it is returned to the blood, makes lymphocytes
tonsils
small masses of lymphatic tissue that form a protective ring in the pharynx and nasal cavity. trapping pathogens that enter the mouth and nose
three types of tonsils
palatine tonsils, lingual tonsils, adenoids (aka pharyngeal tonsils)
where are the palatine tonsils
either side of the throat
where are the lingual tonsils
base of the tongue
where are the adenoids/pharyngeal tonsils
upper part of throat behind the nose (nasopharynx)
thymus
gland that secrets thymosin. diminishes after puberty
mediastinum
space between lungs
thymosin
stimulates the bone marrow to manufacture T lymphocytes
largest lymphatic organ
spleen
spleen functions:
filters blood by destroying worn out red blood cells, produces lymphocytes, stores thrombocytes, reservoir for blood
hemolysis
breaking down of blood cells
which lymphatic organ controls the amount of blood in the body
spleen
liver
does hemolysis and stores healthy erythrocytes
peyer's patches
small bundle of lymphatic tissue in the walls of the small intestine. protect small intestine against pathogens that enter through the digestive tract.
T cell types
cytotoxic(T8), helper T cells(T4), Natural killer cells (NK), Suppressor cells
Cytotoxic (T8)
attach to antigens and destroy them
antigens
proteins on pathogen, unique to specific pathogen
Helper cells (T4)
aid B lymphocytes
NK
recognizes certain sugar patterns on pathogenic cells and targets them
Suppressor cells
slow or stop B lymphocytes when the pathogen has been controlled or destroyed.
B lymphocytes
secrete immunoglobulins and turn into plasma cells. this process is called humoral immunity
Ig G
main defense against infectious invaders in the body. Makes up 7% percent of immunoglobulins
Ig M
fights blood infections. powerful agglutinating agent
IgE
secreted by plasma cells in the skin, tonsils, and respiratory and gastrointenstinal tracts. release bistamine
IgD
found in blood plasma in very small amounts, attach themselves to surfaces of B cells as antigen receptors
IgA
antibodies found in respiratory and gastrointenstinal tracts. secreted in saliva, tears, and breast milk
phagocytosis
phagocytes engulf and digest foreign pathogens