Chapter 24: The Innate and Adaptive Immune Systems

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Pathogens

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24 Terms

1

Pathogens

Organisms that cause infection, such as bacteria, viruses, or fungi.

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2

Restriction factors

Intracellular proteins in bacteria that defend against viruses.

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3

Innate immune response

General defense actions that can involve any cell type in an organism.

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4

Adaptive immune response

Specific immune reactions that are highly tailored to the particular pathogen that induced them.

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5

Lymphocytes

A class of white blood cells involved in the immune response.

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6

B Lymphocytes

Lymphocytes that secrete antibodies that bind specifically to pathogens.

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7

T lymphocytes

Lymphocytes that can directly kill cells infected with pathogens.

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8

Epithelial surfaces

The outermost layers of skin and lining of respiratory, digestive, urinary, and reproductive tracts that provide physical and chemical barriers to pathogen invasion.

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9

Pattern Recognition Receptors (PRRs)

Receptor proteins that recognize specific repeating patterns called pathogen-associated molecular patterns (PAMPs) on pathogens.

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10

Inflammatory response

A response triggered by the activation of PRRs, resulting in the production of extracellular signal molecules that mediate inflammation.

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11

Phagocytic cells

Cells that engulf and destroy pathogens, such as macrophages and neutrophils.

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12

Complement activation

Activation of a system of proteins that target pathogens for phagocytosis or lysis.

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13

B cells

Lymphocytes responsible for producing antibodies that can bind to specific antigens.

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14

Immunoglobulins

Y-shaped proteins produced by B cells and plasma cells that can bind to specific antigens.

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15

T cells

Lymphocytes involved in recognizing specific antigens and coordinating immune responses.

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16

MHC proteins

Cell surface molecules that present antigens to T cells for recognition.

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17

IgM

It is the first antibody produced during an immune response and is particularly effective at activating the complement system.

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18

IgG

It is the most abundant class of antibodies in the bloodstream and is involved in long-term immunity.

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19

IgA

It is primarily found in secretions such as saliva, tears, and breast milk, providing localized protection on mucosal surfaces.

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20

IgE

It is involved in allergic reactions and defense against parasitic infections.

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21

IgD

It is primarily found on the surface of naive B cells, serving as a BCR.

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22

Cytokines

Helper T cells release chemical messengers called cytokines.

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23

Perforin and Granzymes

Cytotoxic substances released by cytotoxic cells.

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24

MHC proteins

It also known as human leukocyte antigens (HLAs) in humans, are cell surface molecules that present antigens to T cells.

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