Tags & Description
What is ATP?
Adenosine triphosphate is an energy source the body uses to power muscles
What are the 3 main methods of ATP production?
ATP-PC System, Anaerobic Glycolysis, and Aerobic Pathway
What does PC stand for?
Phosphocreatine
Why does the body need more ATP to complete muscle movements?
Stored ATP in the muscles starts a contraction, is depleted, and now needs more ATP to continue
Glyco means ______ and lysis means ______
sugar ; breakdown
Anaerobic glycolysis
The breakdown of sugar without oxygen
What determines which ATP method is used?
Intensity and duration of physical activity
What starts the muscle contraction?
Stored ATP
What is ATP-PC short for?
adenosine triphosphate-phosphocreatine
What type of energy supplies powerful short-term energy?
ATP-PC
ADP is ____
Not energy
ATP is ____
Energy
What does creatine phosphate break down into?
Creatine, a phosphate group, and energy
Where is glycogen found?
Muscle cells
Creatine Phosphate (definition)
a high-energy molecule stored only in muscle cells that can add another phosphate group to ADP
Where is creatine phosphate found?
Muscle cells
How does the ATP-PC System add another phosphate group to the ADP?
With creatine phosphate
What breaks down creatine phosphate?
What does ADP combine with to make ATP?
a Phosphate group
What is ATPase?
an enzyme used to combine the extra phosphate from the creatine phosphate with the ADP
What does the ATP creation pathway not require?
Oxygen
The extra phosphate from the creatine phosphate breakdown….
combines with ADP to create a new ATP molecule
What is the next source of energy after the ATP-PC System is depleted?
Anaerobic glycolysis
How long does anaerobic glycolysis last?
~2 min
When does anaerobic glycolysis experience a dip in power?
45 sec
Anaerobic
no oxygen is involved
Glycolysis
the breakdown of glucose into ATP
Glucose
a simple sugar
Motor unit
A group of a single motor neuron and the muscle fibers it stimulates
Where do motor neurons live?
Spinal cord
Axon terminals are…
scattered to the muscle fibers
Axons extend to…
Muscle
Neuron (definition)
nerve cell
Elasticity
muscle”s ability to return to its original length
Extensibility
muscles ability to stretch or extend
Contractility
muscles ability to contract forcefully
Excitability
a muscles ability to respond to stimuli
What triggers muscle movement?
Nerve impulse
Describe the Aerobic Pathways Power and Fuel source
It doesn’t produce as much power as the other two systems, but its fuel source is large and takes a long time to run out
Function of the aerobic pathway system
Allows a person to perform activities that require more endurance
Why dont muscles become acidic after the Electron Transport Chain?
Hydrogen ions are removed in the water by-product
Resultants of the Electron Transport Chain
34 ATP molecules and water as a by-product
In the Krebs cycle, acetyl coenzyme A is broken down into…..?
carbon dioxide which is expelled through breathing and hydrogen ions which are used in the next step
Acetyl coenzyme A (function)
Allows the energy system to continue breaking down glucose into energy
What substance is produced in aerobic glycolysis?
acetyl coenzyme A
The _______ pathway uses _____ which can fix the ______ problem caused by the hydrogen ions
aerobic; oxygen; acidity
Lactate temporarily ______ and ______
reduces acid buildup; stops ATP production
The body creates _____ to correct the acidic environment
lactate
______ cause muscles to become more acidic
Hydrogen ions
By-product of anaerobic glycolysis
hydrogen ions
ATP molecules used to fuel the glycolysis process go through several transformations and produce _________ and _________
pyruvate and hydrogen ions
What does the body do with extra glucose?
Form glycogen to later be stored in the muscles
Pyruvate
a protein the body produces
Steps of the aerobic pathway
Aerobic glycolysis, Krebs Cycle, Electron Transport Chain
Anaerobic Glycolysis System Steps
Glycogen is converted into glucose, The two ATP in the glucose break down into two ADP and two phosphates, Four ATP molecules are created, Two ATP are used for glycolysis fuel and two are for muscle contraction
Anaerobic glycolysis (formal)
a complex conversion of glucose to lactate when oxygen is NOT available
How many molecules of ATP is in 2 glucose molecules
4 molecules
When glycogen is broke down, what do we get?
2 glucose molecules
What is the TOTAL amount of energy the ATP-PC System lasts?
~10-20 sec
How long does the breakdown of creatine phosphate last?
~5-8 sec
How long does the INITIAL ATP-PC energy last?
~6-15 sec
What are the 3 things you need for a muscle to contract?
Energy System, Nerve Impulse, Action Potential
Sarcolemma
a plasma membrane beneath the endomysium
Primary Function of the Sarcolemma
to help with the absorption of calcium that is required for muscle contraction
Neuromuscular junctions
junctions formed by the axon terminals of the motor unit with the sarcolemma in various muscles
Interstitial fluid
allows the neurotransmitter involved in the impulse to work and is found in the synaptic cleft
Acetylcholine (Ach)
a neurotransmitter located in vesicles of the axon terminal at the neuromuscular junction
Another word for impulse is…
Action Potential
What are the three that start a muscle contraction?
Energy Systems, Nervous System, Action Potential
Step 1 of Action Potential Sequence
A nerve impulse travels to the axon terminals of the muscle
Step 2 of Action Potential Sequence
Calcium channels open, allowing calcium to enter the axon terminal
Step 3 of Action Potential Sequence
The presence of calcium causes the release of the enzyme
Step 4 of Action Potential Sequence
ACh (acetylcholine) spreads across the synaptic cleft and attaches to receptors on the sarcolemma
Step 5 of Action Potential Sequence
The ACh (acetylcholine) opens channels in the sarcolemma, allowing sodium (Na+) and potassium (K+) ions to build up in muscle fibers, changing the electrical charge
In Step 5 of the Action Potential Sequence, the change in electrical charge __ and __
triggers myosin and actin to use ATP which is later broken down into ADP ; produces an electrical current or the Action Potential
Step 6 of Action Potential Sequence
AChE (acetylcholinesterase) breaks down the ACh (acetylcholine) in the synaptic cleft, causing the sarcolemma channels to close, stopping muscle fiber contraction
One nerve impulse produces…
one contraction
Muscle cells (myocytes) are also called
muscle fibers
Myocyte Shapes
long and cylindrical
Fascicle
several bundles of individual muscle fibers
What is each fascicle wrapped?
Connective Tissue
Epimysium
a tough outer coat that extends past the muscles tapered end and blends into the tendon, wrapping the skeletal muscle
Perimysium
wraps the muscle fascicles
Endomysium
wraps individual muscle fibers
Mitochondria
part of the cell that produces energy
Skeletal muscle characteristics
striated, multinucleated, 2-3x more mitochondria organelles
Organelle
a subunit within a cell that has a specific function
Sarco-
flesh
Sarcolemma
a plasma membrane that wraps the muscle fibers
Sarco- Lemma-
flesh sheath
Organelles of Muscle Cells/Myocytes
Sarcoplasm, Sarcoplasmic reticulum, Myofibrils
Sarcoplasm
liquid that fills the muscle fiber and is made mostly of water, salts, and proteins
3 Functions of Sarcoplasm
hold inner contents of muscle fibers together, protecting it from damage, allows for chemical reactions to occur, allows for organelle operation
Myofibril
a bundle or group of smaller thread-like fibers called myofilaments
Sarcoplasmic Reticulum
a net-like structure that surrounds each myofibril
Sarcoplasmic Reticulum Function
storing and releasing calcium from the muscle fiber
Myofilaments
thread-like fibers found bundled in the myofibril
Two Types of Myofilament
Thick and thin
Myosin
thick myofilament protein
Actin
thin myofilament protein