DNA/Genetics

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Who discovered the nucleotides?

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38 Terms

1

Who discovered the nucleotides?

Hershey and Chase

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2

Who discovered the way DNA looks?

Watson and Crick

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3

Name the nucleotides for DNA and then RNA

Adenine, Thymine, Guanine, and Cytosine

For RNA, replace Thymine with Uracil

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4

What is the purpose of DNA?

Provides genetic code for a trait

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5

What is semiconservative replication?

In semiconservative replication, the original two strands of the double helix serve as templates for new strands of DNA. When replication is complete, two double-stranded DNA molecules will be present. Each will consist of one original template strand and one newly synthesized strand that is complementary to the template.

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6

What are the enzymes that help semi conservative replication?

DNA Helicase, DNA Primase, DNA Polymerase, and DNA Ligase

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7

What is DNA Helicase?

"Unzips" the DNA
--Breaks the hydrogen bonds between the nucleotides

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8

What is DNA Primase

"Highlighter"
--Highlights an area of where the new half should be built on

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9

What is DNA Polymerase?

--"Builder"
--an enzyme that joins individual nucleotides to produce a new strand of DNA
--builds in a 5' to 3' direction ALWAYS
--proofreads

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10

What is DNA Ligase

"The glue"
--Fills gaps left in the lagging strand
--Fills with OKAZAKI fragments

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11

What is the leading strand?

The strand where replication moves towards the replication (follows helicase)

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12

What is the lagging strand?

The strand where DNA replication moves away from the replication (away from helicase)

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13

what is topoisomerase?

Keeps the DNA from winding together too much

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14

What does 5' and 3' mean?

5' is the end of DNA with a phosphate, and 3' is the end with a deoxyribose sugar

<p>5' is the end of DNA with a phosphate, and 3' is the end with a deoxyribose sugar</p>
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15

What is DNA transcription?

process of writing a copy of a DNA template into mRNA

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16

What is RNA Polymerase?

an enzyme that binds to DNA during transcription and separates or unwinds the DNA strands.

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17

What are the sub-steps to DNA trancription

Initiation, Elongation, and termination

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18

What is Initiation?

RNA polymerase binds to promoter

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19

What is a promoter?

binding site for RNA polymerase

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20

What is elongation?

Codes along the new strand

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21

What is termination?

Signals that the build is done and mRNA is made which goes to the Ribosome and its made into a protien

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22

What is translation?

The transition of DNA from a nucleus to mRNA and going to the ribosome

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23

What is tRNA?

brings an amino acid from the cytoplasm

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24

What is a codon?

a sequence of three nucleotides that together form a unit of genetic code in a DNA or RNA molecule.

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25

What is a Codon Chart?

A chart of codon sequences that tells you what amino acid a codon sequence on the mRNA codes for.

<p>A chart of codon sequences that tells you what amino acid a codon sequence on the mRNA codes for.</p>
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26

What are mutations in DNA

Change in DNA sequence
- have diff consequences relating to the phenotype of the animal

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27

What are the types of mutations

deletion, insertion, substitution, chromosomal mutations, and non disjunction

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28

What is the substitution mutation

Replacement of a single nucleotide by another nucleotide

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29

What is the insertation mutation?

a frameshift mutation, moves all nucleotides from the right of the new nucleotide

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30

What is the deletion mutation?

frameshift mutation, one nucleotide is taken away from a gene or DNA sequence

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31

what is Chromosomal mutations

changes in the chromosomes where parts of the chromosomes are broken and lost during mitosis

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32

what is non disjuction?

When an egg or sperm cell has to many or to less amounts of chromosomes

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33

What is gene expression?

the process by which DNA directs the synthesis of proteins

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34

What is a operon?

a group of genes that operate together

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35

What is a lac operon?

--A collection of genes that are important in coding for enzymes that metabolize lactose.
--If code is being used than it created a enzyme, if not than it doesn't create an enzyme
--if lactose is not present, it doesnt create an enzyme
--saves energy if no enzyme is made

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36

What is eukaryotic regulation?

Exons and Introns

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37

what is an exon?

An expressed sequence of DNA; codes for a protein

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38

what is an intron

non-coding region of DNA, helps prevent mistakes

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