Genetics Final Exam

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DNA

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43 Terms

1

DNA

________ must be replicated in order for cells to divide and pass on genetic information to their daughter cells.

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2

Ligase

________: An enzyme that joins the Okazaki fragments on the lagging strand of DNA during replication.

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3

Topoisomerase

________: An enzyme that relieves the tension caused by the unwinding of DNA during replication.

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4

Translation

________: The process of converting a sequence of nucleotides in mRNA into a sequence of amino acids in a protein.

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5

Termination

________: The final step of translation, where the ribosome reaches a stop codon and the protein is released from the ribosome.

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6

transcription

During ________, a pre- mRNA molecule is synthesized and then modified to form a mature mRNA molecule.

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7

Ribosome

________: A complex molecular machine that reads the sequence of codons in mRNA and catalyzes the formation of peptide bonds between amino acids to form a protein.

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8

elongation

There are three stages of translation: initiation, ________, and termination.

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9

Helicase

________: An enzyme that unwinds the double helix structure of DNA, allowing other enzymes to access the individual strands.

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10

Anticodon

________: A sequence of three nucleotides in tRNA that is complementary to a codon in mRNA and allows the tRNA to recognize and bind to the correct codon.

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11

Primase

________: An enzyme that synthesizes short RNA primers that provide a starting point for DNA synthesis.

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12

Independent assortment

________: the random distribution of homologous chromosomes during meiosis.

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13

5’ Modified guanine cap

protects the mRNA from degradation and helps it bind to ribosomes for translation.

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14

Single strand binding proteins

Proteins that bind to DNA to prevent it from re- forming a double helix.

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15

Mendels two laws of heredity

the Law of Segregation and the Law of Independent Assortment.

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16

DNA synthesis

________ is the process of creating a new strand of DNA from an existing template strand.

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17

RNA splicing

________ is the process of removing introns (non- coding regions) from pre- mRNA and joining together the exons (coding regions) to form mature mRNA.

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18

Random fertilization

________ is a process in sexual reproduction where any sperm can fertilize any egg, resulting in a genetically unique offspring.

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19

TRNA

________: Transfer RNA, a small RNA molecule that carries a specific amino acid to the ribosome and matches it to the appropriate codon in mRNA.

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20

homologous chromosomes

Crossing over is the exchange of genetic material between ________ during meiosis.

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21

Messenger RNA

MRNA: ________, a single- stranded RNA molecule that carries genetic information from DNA to the ribosome.

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22

Codon

________: A sequence of three nucleotides in mRNA that specifies a particular amino acid or a stop signal during translation.

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23

Okazaki fragments

________: Short, discontinuous fragments of DNA synthesized on the lagging strand during replication.

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24

Acetylation

________ neutralizes the positive charge on lysine, loosening the interaction between histones and DNA. Results in more gene expression

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25

DNA polymerase 1

________ has a proofreading function that checks for errors in the newly synthesized DNA strand.

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26

RNA polymerase

________ is an enzyme responsible for the synthesis of RNA from a DNA template during transcription.

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27

Each ________ has an anticodon that matches a specific codon on the mRNA (messenger RNA) strand.

tRNA molecule

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28

poly a tail

a string of adenine nucleotides that also protects the mRNA from degradation and helps regulate its stability and translation efficiency.

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29

Translation

________ in genetics is the process by which the genetic information encoded in messenger RNA (mRNA) is decoded to produce a specific sequence of amino acids, which are the building blocks of proteins.

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30

primase

Priming: An enzyme called ________ adds a short RNA primer to the template strand, which serves as a starting point for DNA synthesis.

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31

Termination

________: The process ends when the DNA polymerase reaches the end of the template strand or encounters a(n) ________ signal.

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32

TRNA

________ (transfer RNA) plays a crucial role in building the polypeptide chain by carrying amino acids to the ribosome.

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33

DNA synthesis

________ is a complex process that is essential for the replication and division of cells.

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34

Amino acid

________: The building blocks of proteins, there are 20 different amino acids that can be combined in various sequences to form a protein.

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35

Pol 1

is a multifunctional enzyme that plays a role in both replication and repair.

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36

Initiation

The process begins when an enzyme called helicase unwinds the double- stranded DNA molecule.

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37

DNA pol 3

has 5 'to 3 'polymerase activity and 3 'to 5 'exonuclease activity, which allows it to proofread and correct errors in dna synthesis

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38

Initiation

The first step of translation, where the ribosome assembles on the mRNA and the first tRNA carrying the amino acid methionine binds to the start codon.

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39

antibodies

An __________ is a protein produced by the immune system that recognizes and binds to specific foreign substances, such as viruses or bacteria, in order to neutralize or eliminate them from the body.

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40

antigens

An __________ is a substance that triggers an immune response, leading to the production of antibodies.

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41

restriction enzymes

A __________ is a type of enzyme that cuts DNA at specific recognition sites.

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42

single nucleotide polymorphisms

Definition: Common genetic variations that occur when a single nucleotide in the DNA sequence is altered. These variations can impact gene function and influence disease susceptibility.

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43

what is recombinant dna

Recombinant DNA is a type of DNA that has been artificially created by combining DNA sequences from different sources. This is typically done in a laboratory setting using techniques such as genetic engineering. The resulting DNA molecule contains genetic material from multiple organisms and can be used to produce proteins or other biological molecules.

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