chapter 18- vaccines

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vaccinations provoke a … immune response

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1

vaccinations provoke a … immune response

primary

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2

the primary immune response, promoted by a vaccination, leads to the formation of … and …

antibodies and memory cells

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3

after vaccination, exposure to the same pathogen allows a rapid and intense … response

secondary

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4

herd immunity is defined as…

immunity in most of the population

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5

due to herd immunity outbreaks are … due to the lack of … individuals

sporadic, susceptible

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6

R° value accounts for…

average # of people an infected person infects

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7

name the type of vaccine…

  • weakened pathogns

  • closely mimics an actual infection

  • confers lifelong cellular and humoral immunity

live attenuated vaccine

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8

name the type of vaccine…

  • safer than live vaccines

  • require repeated booster doses

  • induce mostly humoral immunity

inactivated killed vaccine

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9

name the type of vaccine…

  • uses antigenic fragments to stimulate an immune response

subunit vaccines

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10

toxoids are…

inactivated toxins

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11

the two types of subunit vaccines are…

virus-like particle vaccine and polysaccharide vaccine

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12

name the type of vaccine…

  • resemble intact viruses but do not contain viral genetic material

virus-like particle vaccine

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13

name the type of vaccine…

  • made from molecules in pathogen’s capsule

  • not very immunogenic

polysaccharide vaccine

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14

name the type of vaccine…

  • injected naked DNA produces the protein antigen encoded in the DNA

  • stimulate humoral and cellular immunity

nucleic acid (DNA) vaccine

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15

name the type of vaccine…

  • avirulent viruses or bacteria are genetically modified to deliver gene coding for antigens

recombinant vector (plasmid) vaccine

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16

an adjuvant is a… added to vaccines to improve…

chemical additive, effectiveness

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17

name two adjuvants

alums and monophosphoryl lipid A

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18

name the type of vaccine…

  • easier to make and alter

  • less stable

  • need booster shots

  • requires cold storage

mRNA vaccine

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19

what is a well known mRNA vaccine

COVID-19

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20

a fluorescent-antibody technique is where scientists combine … with …

fluorescent dyes with antibodies

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21
<p>direct fluorescent-antibody (FA) tests are used to…</p>

direct fluorescent-antibody (FA) tests are used to…

identify a microorganism in a clinical specimen

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22
<p>indirect fluorescent-antibody (FA) tests are used to…</p>

indirect fluorescent-antibody (FA) tests are used to…

detect a specific antibody in serum

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23
<p>explain the three stages of the “Fluorescence-Activated Cell Sorter (FACS)”</p>

explain the three stages of the “Fluorescence-Activated Cell Sorter (FACS)”

  1. laser beam strikes a droplet containing a cell

  2. detector determines size and fluoresce of surface molecules

  3. imparts a charge to the cell, separating cells

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