Chapter 8: Cellular Reproduction

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Sarcomas

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50 Terms

1

Sarcomas

________ are cancers arising in muscle or connective tissue, particularly in bone or cartilage.

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Carcinogenesis

________ is a gradual process that requires the accumulation of multiple mutations over time.

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3

Centrosome

A(n) ________ is the primary microtubule organizing center of a cell.

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4

Kinases

________ are active in the removal of the nuclear membrane and the condensation of the chromosomes early in prophase.

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5

Chemotherapy

________ kills cancer cells that have spread throughout the body by damaging their DNA or interfering with DNA synthesis.

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Sun Exposure

________ is a major factor in the development of many skin cancers, including the most dangerous type, melanoma.

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Genetic Tests

________ can detect the presence of specific alleles in many of the genes mentioned.

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8

G2

________ is the phase following DNA synthesis.

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Mitosis

________ is usually followed by cytokinesis, which is the division of the cytoplasm.

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Immunotherapy

________ uses the patient's own immune system cells to target cancer cells for destruction.

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11

Hormones Act

________ on tissues at a distance and can signal cells to divide, such as estrogen- stimulating cells lining the uterus to divide in preparation for implantation.

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BRCA2

________ was later discovered to be associated with some forms of breast cancer.

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13

Apoptosis

________ is important for maintaining homeostasis in the body.

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Cellular Reproduction

________ continues throughout a person's life, helping to grow new tissues and repair damaged ones.

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15

Binary Fission

________ is a form of asexual reproduction, which means that the new cells are identical to the original parent cell.

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Telomeres

________ are caps at the end of chromosomes that protect them from unraveling.

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17

Surgery

________ is often the first line of treatment for solid tumors, especially when detected early.

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18

Monoclonal Antibodies

________ and vaccines are being developed to act specifically on cancer cells and prime the immune system to identify and destroy them.

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19

Independent Daughter

The contractile ring continues to separate the cytoplasm until there are two ________ cells.

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20

Spindle Apparatus

During mitosis, a(n) ________ forms and separates the sister chromatids of each duplicated chromosome.

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21

Carcinomas

________ are cancers of the epithelial tissue lining organs.

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Chromatin

________ is organized into nucleosomes, which are bead- like structures consisting of DNA wrapped around a core of eight histone proteins.

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G

________ stands for "growth "because the cell is metabolically active during these phases.

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Spindle

A(n) ________ is used to pull the chromatids apart.

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Fibroblasts

________ and cells lining the cavities of the lungs, liver, uterus, and kidneys can divide when stimulated.

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Humans

________ begin life as a single cell, but through cellular reproduction, they grow into an organism consisting of trillions of cells in less than 10 months.

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Microtubules

________ play an important role in cell division, by helping to move the chromosomes around the cell.

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Radiation Therapy

________ directs high- energy beams at the tumor to kill cancer cells within a specific area.

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Leukemias

________ are cancers of the blood.

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Tumor Suppressor Genes

________ code for proteins that inhibit the cell cycle and promote apoptosis.

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Series of Changes

During apoptosis, cells go through a(n) ________ that lead to their death.

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BRCA1

________ and BRCA2 are genes associated with breast cancer.

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Nucleosomes

________ are arranged in a zigzag fashion, and then they are folded into loops for further compaction.

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Gene Amplification

________ is seen much more frequently in cancer cells than in normal cells.

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35

DNA Replication

________ occurs in the middle of interphase.

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36

Translocations

________ can disrupt genes that regulate the cell cycle, which can lead to uncontrolled cell growth.

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Band of Actin Filaments

A(n) ________ called the contractile ring forms a circular constriction between two daughter cells.

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Retinoblastoma

________ first appears as a white mass in the retina.

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Contact Inhibition

________ prevents cells from overgrowing within the body and halts the cell cycle.

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40

DNA Replication

The process of copying DNA is called ____.

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41

Chromatin

____ is the complex of DNA and proteins that makes up chromosomes.

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42

Histone

____ are proteins that help to package DNA into chromosomes.

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43

Nucleosomes

____ are the basic units of chromatin.

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44

Sister Chromatids

____ are two identical copies of a chromosome that are created during DNA replication.

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45

Centromere

The ____ is the region of a chromosome that holds the two sister chromatids together.

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46

Cell Cycle

The ____ is the series of events that take place in a cell as it grows and divides.

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47

Spindle

The ____ is a structure that helps to segregate the chromosomes during cell division.

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48

Centrosome

The ____ is a structure that contains the centrioles, which are involved in the formation of the spindle.

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49

Cell Plate

The ____ is a structure that forms between the two daughter cells during cell division.

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50

Checkpoints

____ are points in the cell cycle where the cell checks to make sure that the DNA has been replicated correctly before it proceeds to the next stage.

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