Sarcomas
________ are cancers arising in muscle or connective tissue, particularly in bone or cartilage.
Carcinogenesis
________ is a gradual process that requires the accumulation of multiple mutations over time.
Centrosome
A(n) ________ is the primary microtubule organizing center of a cell.
Kinases
________ are active in the removal of the nuclear membrane and the condensation of the chromosomes early in prophase.
Chemotherapy
________ kills cancer cells that have spread throughout the body by damaging their DNA or interfering with DNA synthesis.
Sun Exposure
________ is a major factor in the development of many skin cancers, including the most dangerous type, melanoma.
Genetic Tests
________ can detect the presence of specific alleles in many of the genes mentioned.
G2
________ is the phase following DNA synthesis.
Mitosis
________ is usually followed by cytokinesis, which is the division of the cytoplasm.
Immunotherapy
________ uses the patient's own immune system cells to target cancer cells for destruction.
Hormones Act
________ on tissues at a distance and can signal cells to divide, such as estrogen- stimulating cells lining the uterus to divide in preparation for implantation.
BRCA2
________ was later discovered to be associated with some forms of breast cancer.
Apoptosis
________ is important for maintaining homeostasis in the body.
Cellular Reproduction
________ continues throughout a person's life, helping to grow new tissues and repair damaged ones.
Binary Fission
________ is a form of asexual reproduction, which means that the new cells are identical to the original parent cell.
Telomeres
________ are caps at the end of chromosomes that protect them from unraveling.
Surgery
________ is often the first line of treatment for solid tumors, especially when detected early.
Monoclonal Antibodies
________ and vaccines are being developed to act specifically on cancer cells and prime the immune system to identify and destroy them.
Independent Daughter
The contractile ring continues to separate the cytoplasm until there are two ________ cells.
Spindle Apparatus
During mitosis, a(n) ________ forms and separates the sister chromatids of each duplicated chromosome.
Carcinomas
________ are cancers of the epithelial tissue lining organs.
Chromatin
________ is organized into nucleosomes, which are bead- like structures consisting of DNA wrapped around a core of eight histone proteins.
G
________ stands for "growth "because the cell is metabolically active during these phases.
Spindle
A(n) ________ is used to pull the chromatids apart.
Fibroblasts
________ and cells lining the cavities of the lungs, liver, uterus, and kidneys can divide when stimulated.
Humans
________ begin life as a single cell, but through cellular reproduction, they grow into an organism consisting of trillions of cells in less than 10 months.
Microtubules
________ play an important role in cell division, by helping to move the chromosomes around the cell.
Radiation Therapy
________ directs high- energy beams at the tumor to kill cancer cells within a specific area.
Leukemias
________ are cancers of the blood.
Tumor Suppressor Genes
________ code for proteins that inhibit the cell cycle and promote apoptosis.
Series of Changes
During apoptosis, cells go through a(n) ________ that lead to their death.
BRCA1
________ and BRCA2 are genes associated with breast cancer.
Nucleosomes
________ are arranged in a zigzag fashion, and then they are folded into loops for further compaction.
Gene Amplification
________ is seen much more frequently in cancer cells than in normal cells.
DNA Replication
________ occurs in the middle of interphase.
Translocations
________ can disrupt genes that regulate the cell cycle, which can lead to uncontrolled cell growth.
Band of Actin Filaments
A(n) ________ called the contractile ring forms a circular constriction between two daughter cells.
Retinoblastoma
________ first appears as a white mass in the retina.
Contact Inhibition
________ prevents cells from overgrowing within the body and halts the cell cycle.
DNA Replication
The process of copying DNA is called ____.
Chromatin
____ is the complex of DNA and proteins that makes up chromosomes.
Histone
____ are proteins that help to package DNA into chromosomes.
Nucleosomes
____ are the basic units of chromatin.
Sister Chromatids
____ are two identical copies of a chromosome that are created during DNA replication.
Centromere
The ____ is the region of a chromosome that holds the two sister chromatids together.
Cell Cycle
The ____ is the series of events that take place in a cell as it grows and divides.
Spindle
The ____ is a structure that helps to segregate the chromosomes during cell division.
Centrosome
The ____ is a structure that contains the centrioles, which are involved in the formation of the spindle.
Cell Plate
The ____ is a structure that forms between the two daughter cells during cell division.
Checkpoints
____ are points in the cell cycle where the cell checks to make sure that the DNA has been replicated correctly before it proceeds to the next stage.