6. Virology II - PID

The ability of a Virus to cause disease in a host

A virus that causes disease.

The manner/mechanism of development of a disease.

The quantitative or relative measure of the degree of pathogenicity of an infecting virus.

Not virulent.

Virulence (IS/IS NOT) an absolute property of a virus.

Virulence is dependent on many ________.

Virulence is dependent on factors related to the ______, host, and other factors.

Virulence is dependent on factors related to the _______, virus, and other factors.

The dose of the virus required to cause death in 50% of animals.

A lower LD50 is a (MORE/LESS) virulent virus.

A higher LD50 is a (MORE/LESS) virulent virus.

Virus A has an LD50 of 15, while Virus B has an LD50 of 40. Virus (A/B) is more virulent

Route of entry via a bite (by an arthropod or infected animal) or exposure to a contaminated needle.

Presence of a virus in the blood.

Initial entry of a virus into the blood

Virus has replicated/multiplied in major organs and re-entered the blood stream.

An infection that has spread beyond the primary site of infection.

An infection that has infected a number of organs or tissues.

Viruses can spread via _________ from the periphery, through receptors in the olfactory epithelium, or by crossing blood brain barrier.

A virus that can infect neural cells.

Virus that enters the CNS after infection of a peripheral site.

A virus that causes disease of nervous tissue, manifesting as neurological symptoms and often death.

A virus can use a ___________ as a "trojan horse" to cross blood-tissue barriers.

The affinity of a virus for a particular host tissue

Viruses that can replicate in more than one host organ/tissue.

Lysis occurs (BEFORE/AFTER) completion of viral replication.

Apoptosis occurs (BEFORE/AFTER) completion of viral replication.

Virus that can cause cancer

Some viruses do not cause immediate death of an infected host cell, but rather cause a ________ _________ that can result in low titer shedding for months to years.

Some virus replication strategies result in atrophy or destruction of specific immune system cells, resulting in

____________ infections usually result in intensive shedding over a short period.

___________ infections can result in shedding at low titers for months to years.

The release of infectious virions.

Viral injury to the skin can be localized or __________.

Viral injury to the skin can be disseminated or _________.

Reddening of the skin.

Term for destructing or bursting

Term for the death of body tissue

The killing/devouring of neuronal cells by phagocytic cells

Bubbles found in cells

Material composing a sheath around nerves.

Viral infection of the hemopoietic system can cause DIC:

Virus that causes developmental defects of embryo or fetus after in-utero infection.