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What are common s/sx of stroke
Unilateral paralysis
Unilateral numbness
Language disturbances
Change in mental status
Visuospatial neglect
Blurred vision
Stroke Risk Factors
HTN
DM
Afib
NIH stroke scale
Mild= 0-4
Moderate= 5-9
Severe= 10 or >
Ischemic vs Hemorrhagic stroke
Hemorrhagic has bleeding in CT
ACLS Stroke Algorithm
Identify signs & Symptoms of stroke
Activate EMS
O2 if Pox <94
Check glucose bc hypo/hyper glycemia can mimic stroke
Immediate general assessment & stabilization
Assess vital signs,labs, ABCs
O2 if Pox <94
Immediate neurologic assessment by stroke team
Establish time of symptom onset or last known normal
CT scan to evaluate for hemorrhage
Treatment algorithm
Who Can be treated with fibrinolytic within 3 hours from symptom onset or last known normal
→Measurable neurologic damage
→18 & up
Who Can be treated with fibrinolytic within 3-4.5 hours
→80 or younger, no H/O diabetes or CVA, not on DOACs
→NIHSS 25 or less
Patients who CANNOT be treated with fibrinolytics within 3-4.5 hours from symptom onset
→Systolic BP>185mmHg or diastolic >110 mg (you can lower it tho)
→Platelet count <100,000
→ INR >1.7, aPTT>40, PT>15
→LMWH treatment dose within 24 hours
→DOAC within 48 hours
→ Current warfarin use & INR >1.7
How to lower BP so they can qualify for fibrinolytic
→Nicardipine
→Labetalol
→Clevidipine
Alteplase Administration
0.9 mg/kg (max dose= 90 mg)
→10% bolus over 1 min
→90% infused over 1 hour
Tenecteplase administration
0.25 mg/kg single IV bolus over 5 seconds (25 mg max)
Serious potential side effect with fibrinolytic
Intracerebral hemorrhage
angioedema
What med would you hold if someone has angioedema
ACEI & ARNI
How to minimize risk for ICH
Hold antiplatelets & anticoags for 24 hours after administering fibrinolytic
Repeat head CT prior to starting AP and AC
How long maintain passive hypertension after treatment ?
Maintain BP <180/105 for at least the first 24 hours after treatment
When can you transition to oral therapy
Must pass swallow study
What should their blood sugar be between
140-180
Avoid hypoglycemia (<60)