Acute Stroke

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What are common s/sx of stroke

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1

What are common s/sx of stroke

Unilateral paralysis

Unilateral numbness

Language disturbances

Change in mental status

Visuospatial neglect

Blurred vision

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2

Stroke Risk Factors

HTN

DM

Afib

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3

NIH stroke scale

Mild= 0-4

Moderate= 5-9

Severe= 10 or >

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4

Ischemic vs Hemorrhagic stroke

Hemorrhagic has bleeding in CT

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5

ACLS Stroke Algorithm

  1. Identify signs & Symptoms of stroke

  2. Activate EMS 

    1. O2 if Pox <94

    2. Check glucose bc hypo/hyper glycemia can mimic stroke  

  3. Immediate general assessment & stabilization

    1. Assess vital signs,labs, ABCs

    2. O2 if Pox <94

  4. Immediate neurologic assessment by stroke team

    1. Establish time of symptom onset or last known normal

    2. CT scan to evaluate for hemorrhage 

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6

Treatment algorithm

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7

Who Can be treated with fibrinolytic within 3 hours from symptom onset or last known normal

→Measurable neurologic damage

→18 & up

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8

Who Can be treated with fibrinolytic within 3-4.5 hours

→80 or younger, no H/O diabetes or CVA, not on DOACs

→NIHSS 25 or less

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9

Patients who CANNOT be treated with fibrinolytics within 3-4.5 hours from symptom onset

→Systolic BP>185mmHg or diastolic >110 mg (you can lower it tho)

→Platelet count <100,000

INR >1.7, aPTT>40, PT>15

→LMWH treatment dose within 24 hours

→DOAC within 48 hours

→ Current warfarin use & INR >1.7

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10

How to lower BP so they can qualify for fibrinolytic

→Nicardipine

→Labetalol

→Clevidipine

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11

Alteplase Administration

0.9 mg/kg (max dose= 90 mg)

→10% bolus over 1 min

→90% infused over 1 hour

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12

Tenecteplase administration

0.25 mg/kg single IV bolus over 5 seconds (25 mg max)

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13

Serious potential side effect with fibrinolytic

Intracerebral hemorrhage

angioedema

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14

What med would you hold if someone has angioedema

ACEI & ARNI

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15

How to minimize risk for ICH

Hold antiplatelets & anticoags for 24 hours after administering fibrinolytic

Repeat head CT prior to starting AP and AC

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16

How long maintain passive hypertension after treatment ?

Maintain BP <180/105 for at least the first 24 hours after treatment

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17

When can you transition to oral therapy

Must pass swallow study

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18

What should their blood sugar be between

140-180

Avoid hypoglycemia (<60)

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