DNA Replication

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DNA Replication

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23 Terms

1

DNA Replication

the process of making identical copies of DNA before cell division

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2

Replication Origin

Specific sequence of DNA where DNA synthesis begins.

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3

Semiconservative replication

Each half of an original DNA molecule serves as a template for a new strand, and the two new DNA molecules each have one old and one new strand.

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4

DNA helicase

An enzyme that unwinds the double helix of DNA and separates the DNA strands in preparation for DNA replication.

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5

DNA Polymerase

Enzyme involved in DNA replication that joins individual nucleotides to produce a DNA molecule

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6

RNA Primer

Sequence of RNA nucleotides bound to a region of single

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7

leading strand

the strand of DNA that is continuously synthesized into the replication fork.

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8

lagging strand

The strand that is synthesized away from the replication fork , in fragments using sections called Okazaki fragments.

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9

Okazaki fragments

Small fragments of DNA produced on the lagging strand during DNA replication, joined later by DNA ligase to form a complete strand.

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10

DNA ligase

enzyme which connects the individual okazaki fragments on the lagging strand by forming covalent bonds

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11

direction of replication

5' to 3' direction; In DNA synthesis, DNA strands always elongate in a 5' to 3' direction.

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12

double helix

The form of DNA, referring to its two strands wound into a spiral shape.

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13

Primase

An enzyme that creates a short RNA primer for initiation of DNA replication.

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14

deoxyribonucleic acid

A molecule that consists of nucleotide monomers used for transmitting genetic information from one generation to the next

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15

nucleic acid

Macromolecules that includes DNA and RNA.

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16

nucleotide

A subunit of nucleic acids formed from a simple sugar, a phosphate group, and a nitrogenous base.

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17

adenine

A nitrogen base found in DNA and RNA. It pairs with thymine in DNA and with uracil in RNA

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18

guanine

A nitrogen base found in both DNA and RNA; pairs only with cytosine.

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19

thymine

A nucleotide that pairs with adenine. Found only in DNA.

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20

cytosine

A nitrogenous base found in DNA and RNA; pairs with guanine

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21

hydrogen bond

A weak chemical bond used to hold complementary base pairs together

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22

base pairs

Any of the pairs formed between complementary bases in the two nucleotide chains of DNA, such as A

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23

Replication fork

Y shaped structure formed during DNA replication

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