wakako

adverse effects of osmotic diuretics

acute renal failure and lactic acidosis

indication of carbonic anhydrase inhibitor

glaucoma, epilepsy, edema

adverse effect of carbonic anhydrase inhibitor

metabolic acidosis

indication of SGLT2 inibitor

diabetes, heart failure

highly potent loop diuretic

furosemide

contraindication of loop diuretics

hypokalemia

adverse effect of loop diuretics

hypokalemia, hyperuricemia, glucose intolerance

moderately potent thiazides

trichlormethiazide

thiazides reduce urine volume if a patient has...

diabetes insipidus

indication of thiazides

hypertension, edema

adverse effect of thiazides

hypokalemia, hyponatremia, aplastic anemia, hyperuricemia, glucose intolerance, pulmonary edema

an example of mineralcorticoid receptor blocker

spirinolactone

contraindication of mineralcorticoid receptor blocker (spironolactone)

hyperkalemia, renal failure (anuria)

adverse effect of spironolactone (mineralcorticoid receptor blocker)

hyperkalemia, gynecomastia

contraindication of Na channel blockers

hyperkalemia

adverse effect of Na channel blockers

hyperkalemia, acute renal failure

adverse effect of vasopressin receptor antagonist

hypernatremia, thromboembolism, renal failure, ventricular fibrillation, ventricular tachycardia, liver dysfunction

thiazides and loop diuretics are both used as:

hypertension, edema, chronic heart failure, acute pulmonary edema

indication of ACE inhibitor

hypertension, chronic heart failure

contraindication of ACE inhibitor

bilateral renal artery stenosis

adverse effect of ACE inhibitor

dry cough, angioedema, hyperkalemia, nephrotic syndrome, acute renal failure

adverse effect of ARB

angioedema, hyperkalemia, shock, syncope, acute renal failure, liver dysfunction, jaundice, hepatitis, hypoglycemia, rhabdonyolysis

name 2 DHP Ca antagonist drugs

nifedipine, amlodipine

adverse effect of -dipines (DHP Ca antagonist)

tachycardia, palpitaitons

indication of verapamil

supraventricular tachycardia, angina pectoris (anti-dysrhythmic action)

adverse effect of verapamil

bradycardia, AV block

indication of diltiazem

hypertention, angina pectoris, supracentricular tachycardia

function of adrenoceptor alpha 1

BP elevation, pupil dilation, suppression of urination

function of adrenoceptor alpha 2

negative feedback of nerve endings

function of adrenoceptor beta 1

increased heart rate

function of adrenoceptor beta 2

BP decrease, bronchodilation

function of adrenoceptor beta 3

urination

indications of selective alpha adrenoceptor antagonist

hypertension, dysuria

adverse effect of alpha adrenoceptor antagonist

orthostatic hypotesion

non-selective beta adrenoceptor antagonist suffix

• olol

indication of -olols

hypertention, angina pectoris, dysrhythmia

contraindication of -olols

asthma, pregnancy

adverse effect of -olols

asthma, dyspnea, atypical angina, bradycardia

2 anti-hypertensives for pregnant

methyldopa, hydralazine

supraventricular tachyarrhythmia

sinus tachycardia, atrial premature contraction, atrial flutter, paroximal supraventricular tachycardia, atrial fibrillation

ventricular tachyarrhythmia

ventricular tachycardia, ventricular fibrillation, ventricular premature contraction

bradyarrhythmia

sinusoidal failure syndrome, AV block

class Ia antidysrhythmic drug treats

tachyarrhythmia, prevents atrial fibrillation

class Ib antidysrhythmic drug treats

ventricular tachyarrhythmia

class Ic antidysrhythmic drug treats

tachyarrhythmia, prevention of atrial fibrillation

beta blockers are also known as class ( ) antidysrhythmic drug

II

class III antidysrhythmic drug treats

ventricular tachycardia, ventricular fibrillation

class IV antidysrhythmic drug treats

supraventricular arrhythmias

drugs used for chronic angina

organic nitrates, aspirin, statin, beta blockers, calcium blockers

drugs for TREATING variant angina

organic nitrates

drugs for PREVENTING variant angina

calcium blockers and nitrates

drugs for treating AMI

nitrates, aspirin, beta blockers, anti-platelet, anticoagulant, thromnolytic drug

adverse effect of fibrate

myositis-like syndrome, gallstones

contraindication of aspirin

bleeding tendency, peptic ulcer, history of aspirin-induced asthma

adverse effects of aspirin

peptic ulcer, shock, astma-induced asthma, anaphylaxis, toxic necrosis

indication of digitalis glycosides

congestive heart failure, supraventricular tachyarrhythmia

adverse effect of digitalis glycosides

digitalis intoxication (arrhythmia, dizziness, nausea, etc.)

indication of PDE inhibitor

acute heart failure

adverse effect of PDE inhibitor

arrhythmia

indication of beta stimulant

acute heart failure, shock, chronic heart failure

adverse effect of beta stimulant

arrhythmia

indication of ANP

acute heart failure

adverse effect of ANP

shock, bradycardia, arrhythmia

thymidic acid is consisted of:

thymine, deoxyribose, phosphate

side effect of mercaptourine

myelosuppression

side effect of methotrexate

interstitial pneumonia

side effect of fluorouracil

myelosuppresssion and stomatitis

side effects of pyrimidine analogue

myelosuppression, CNS symptoms, liver dysfunction, interstitial pneumonia

side effect of cisplatin

nephrotoxic syndrome, severe nausea/vomiting, peripheral neuropathy, hearing loss, myelosuppression

side effects of anthracyclines

myelosuppression, cardiotoxicity

side effect of cyclophosphamide

hemorrhagic cystitis

side effect of bleomycin

lung disorders

all-trans retinoic acid is used for treating

acute promyelocytic leukemia