The Immune System 

- outside: non specific 

- inside: non specific 

- inside- specific "immune response" 

- B LYMPHOCYTES: proliferate in the bone marrow 

- T LYMPHOCYTES: mature in the thymus 

- ANTIGENS: foreign molecules hat elicit a response  by lymphocytes (portion of pathogen) 

- ANTIBODIES: soluble proteins secreted by B cells during an immune response 

- PATHOGEN: what makes you sick; bacteria, virus, fungus

- BOR  CELL ACTIVATION: occurs when an antigen binds to a b or T cell 

- CLONAL SELECTION: B cells form two clones of cells in a process 

   - EFFECTOR CELLS: combat the antigen by producing antibodies specific to that antigen

   - MEMORY CELLS: long lived, bear receptors for the same antigen T cell receptors bind antigens that are displayed by antigen presenting cells on their MCHs

Adaptive immunity defends against infection of body fluids and body cells 

- HUMORAL IMMUNE RECEPTORS: involves the activation and clonal selection of effector B cells 

- HELPER T CELLS: aid both responses 

-CYTOXIC T CELLS: bind top class/ MHC molecules displaying aristogenic fragments on the surface of infected body cells 

In adaptive immunity, receptors provide pathogen specific recognition 

- MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULES: proteins that are the product of genes. there are two types: 

   - CLASS I MHCS: found on almost all cells of the body except RBCs

   -CLASS II MHCS: made by some cells of the immune system, including dendritic cells, macrophages, and B cells 

- each B or T cell responds to only 1 antigen