space between the metaphysis and epiphysis
-only in living individuals, seen in X-Rays
Metaphysis
where diaphysis and epiphysis meet
Collagen in bone
type 2
Osteoblasts
build bone by secreting osteoid
osteoid
unmineralized bone matrix
Osteoclasts
clear away/break bone
-repair via remodelling
Osteocytes
mature bone cells
-osteoblasts trapped in bone matrix
Lacunae
pores that contain osteocytes
Function of osteocytes
bone maintenance and communication
-respond to need for more/less minerals
-alert BMU to damaged bone
Layers of bone
periosteum and endosteum
Periosteum
fibrous membrane covering a bone
Endosteum
lining of the medullary cavity
Lamellar bone
mature bone
lamellae
sheets of mature bone, 3-7 microns thick
Haversian canal
central, longitudinal canals of bone that carry blood vessels and nerves to deliver nutrients and signals through bone matrix
Osteon
basic unit of lamellar bone
-Includes osteocyte, haversian canal, and circular sheets of lamellae
Volkmann's Canals
transverse canals that connect Haversian canals, also carry blood vessels and nerves
endochondral ossification
process in which bone forms by replacing hyaline cartilage
1. Bone collar formation
2. Calcification of cartilage, cavitation begins
3. spongy bone forms in center shaft
4. Medullary cavity forms, SOCs appear, ossification continues
5. Ossification of epiphyses, hyaline cartilage only remains in epiphyseal plate and articular cartilage
intramembranous ossification
bone develops from a fibrous membrane
1. Mesenchymal stem cells differentiate into osteoblasts and form ossification center
2. Osteoid secreted and calcifies which traps osteoblasts to become osteocytes
3. Osteoid laid in random pattern, forms woven bone. Mesenchyme condenses on outer layer of woven bone and becomes periosteum
4. Lamellar bone replaces woven bone forming compact bone sheets and red marrow appears
Types of bones
compact (dense/cortical) and spongy (trabecular/cancellous)
functions of skeleton
Hematopoiesis, mineral/fat storage, support, protection, movement
stored in medullary cavity, mostly fat
yellow marrow
stored within cancellous tissue
red marrow
minerals in bone
mostly calcium and phosphate
Trabecular bone makes up
flat bones, articular ends of long bones
Compact bone makes up
external surfaces of bone, shaft of long bone
Bones longer than they are wide
long bone
generally cube shaped bones, or bones that form within tendons
short bones
thin, flattened and slightly curved bones
flat bones
bones with complicated shapes
irregular bones
Long bones make up the
appendicular skeleton
short bone examples
carpals, tarsals, and patella
flat bone examples
skull, ribs, sternum, and pelvis
irregular bone examples
vertebrae, mandible and parts of the splanchnocranium
intramembranous: L & R plates
endochondral: fusion of plates
vomer articulations
sphenoid, ethmoid, palatines, maxilla
Inferior nasal concha(e) ossification
endochondral: L & R
inferior nasal concha articulations
lacrimals, ethmoid, palatines, maxilla
auditory ossicles
stapes, incus, malleus
Supraorbital foramen
frontal bone; supraorbital nerve, artery, and vein
optic canal
Sphenoid; optic nerve and ophthalmic artery
carotid canal
temporal; internal carotid nerve and artery
hypoglossal canal
occipital; hypoglossal nerve
foramen magnum
occipital; spinal cord, vertebral arteries
mental foramen
mandible; mental nerve, artery, and vein
crown
1
root
2
enamel
3
dentin
4
pulp cavity
5
periodontal ligament
7
cementum
border between yellow tooth root and pink periodontal ligament
enamel composition
96% inorganic hydroxyapatite, hardest tissue in body, organic: proteins and water
dentin composition
70% inorganic, 30% organic
cementum composition
nonvascular bone, rich in collagen fibers
Antimere
left and right symmetry
isomere
top and bottom symmetry
Incisal surface
cutting edge, biting surface of incisors and canines
occlusal surface
chewing surface of premolars and molars
lingulum
ridge of enamel at base of tooth on lingual surface
amelogenesis
process of enamel formation
ameloblasts
enamel forming cells
dentinogenesis
process of dentin formation
odontoblasts
dentin forming cells
4 stages of tooth development
bud, cap, bell, eruption
bud stage
8th week; dental laminae give rise to tooth buds
cap stage
11th week; invagination of buds create caps (called tooth germs by the end). Tooth crown, dentin, pulp cavity, cementum and periodontal ligament all formed
bell stage
12th week; hard tissue begins to form, odontoblasts and ameloblasts are differentiated
Cervical vertebrae
7, make up neck
thoracic vertebrae
12, make up upper back (connections for ribs)
lumbar vertebrae
5, sometimes 6, make up lower back
sacrum
5 fused verts (variable #: 4-6)
coccyx
4 fused verts, most variable in #
Kyphosis
anterior pinching of the thoracic, sacral, and caudal vertebrae
Lordosis
posterior pinching of the cervical and lumbar vertebrae
Fibrous joint
strong and stiff fibrous cartilage that offers little movement
synovial joint
cartilage covered articular surfaces separated and lubricated by synovial fluid, offers free movement
fibrous
type of joint found between vertebral disks
synovial
type of joint found between spinus processes
annulis fibrosis
dense fibrous connection that seals in soft nucleus of intervertebral disks
intervertebral disk
fibrous joint between the bodies of two vertebrae
nucleus pulposus
soft inner center of intervertebral disks made of water and loose collagen fibers
Vertebrae ossification
endochondral
POCs of vertebrae
body, L & R halves of neural arch
SOCs of vertebrae
superior and inferior border of the body, tip of the spinus process, L & R tips of transverse processes
neural arch halves fuse together
1-3 years
neural arch fuses to body
3-6 years
vertebral ligaments
anterior and posterior longitudinal, interspinal, supraspinus, and ligamentum flavum