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MLS Clinical Chemistry Exam 1

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Normal

increased alpha zones; acute inflammation

decreased alpha 1; emphysema, lung and liver disease

increased albumin, bridge from gamma to beta; cirrhosis

Spike in gamma (M spike); multiple myeloma

increased albumin, alpha 2, beta, gamma; nephrosis

PP2

~72%

~85%

~15%

5.6 mmol/L

~53%

>95%

<5%

~95%

~28%

~72%

28%

2,4s

1,3s

trend

pt 3: 1,2s; Pt. 7-10: 4,1s

shift

10x

red circle

blue circle

The variable side chain

18, 19, 20

9, 10

1, 2, 3, 4, 5, 6, 7, 8, 11

12, 13, 14, 15, 16, 17

far left, serine, 1

far right, lysine, 7

OC-NH bonds between amino acids

disulfide