Contraction is the specific function of:
muscle tissue
Skeletal muscle is considered
voluntary, striated
Skeletal muscle fibers are also known as
myofibers
Nervous tissue includes neurons and the supporting cells known as
neuroglia
What are the three major types of muscle tissue?
Smooth, cardiac, and skeletal
Glands are derived from _________ tissue.
epithelial
Exocrine glands secrete products into ______.
ducts
Endocrine glands secrete ________ directly into the blood.
hormones
Flat epithelial cells are characterized as _, cells that are TALLER than they are wide are characterized as _, and cells that are AS TALL as they are wide are ________________.
squamous, columnar, cuboidal
Capillary walls are ________ __________ ______________.
simple squamous epithelium
The type of tissue that covers surfaces, forms membranes and glands is:
epithelial tissue
Secreting mucus is the function of ________ cells.
goblet
Connective tissue includes:
bone, blood, and cartilage
Goblet cells can be found in:
columnar epithelium
Blood is considered ___________ tissue.
connective
Where are ciliated epithelial cells are found?
Respiratory passageways and uterine tubes
The cells in cartilage are called ______________.
chondrocytes
In addition to connective tissue proper, the other primary types of connective tissues are: _, _, and ___________.
Blood, bone, and cartilage
The matrix of connective tissue is __________.
extracellular
Intracellular fluid is approximately
65% of total body water
What is the body's normal response when carbohydrates are ingested?
Blood glucose levels increase and insulin release is stimulated
How does the graph show that the normal negative feedback control is NOT occurring in untreated Type I diabetes mellitus?
Glucose levels do not decrease to normal levels because insulin is not released.
What makes a hypothesis scientific?
It is testable
Match the example items with the correct primary tissue type: Neuroglia: ______________ Tendons: ________________ Cardiac: ________________ Simple squamous: __________________
Nervous Connective Muscular Epithelial
Low levels of estrogen stimulate the release of GnRH from ___________.
hypothalamus
After ovulation, progesterone is produced by _____________.
the corpus luteum
The DNA in the nucleus of cells makes up structures known as chromosomes. Chromosomes are divided into segments referred to as genes. Genes are very important because they encode an organism's genetic information. What does an organism's genetic information specify?
What protein an organism makes
All _________ are composed of multiple tissues. For example, skin comprises specific types of muscle, nervous, epithelial, and connective tissues.
organs
Alport's syndrome, a disease affecting collagen formation associated with basement membranes, will most likely affect which of the following functions?
The regulation of soluble substances into and out of the body
Fluid contacting multiple blood cell membranes, connective tissue matrix, and cerebrospinal fluid is extracellular or intracellular compartment?
Extracellular compartment
Fluid contacting mitochondrial membranes, fluid surrounding the cytoskeleton, cytosol, and ATP produced by the cell is extracellular or intracellular compartment?
Intracellular compartment
What role does this tissue play in glucose regulation?
It is a major tissue involved with glucose storage in the presence of insulin.
Which of the following statements regarding collagen fibers is false?
They are intracellular proteins.
Calcium phosphate impregnating a matrix, which surrounds cells nourished by blood in canaliculi, describes which of the following?
Bone
The cells of which of the following tissues contain many nuclei?
Skeletal muscle
Regarding the set point of a negative feedback loop, which of the following statements is false?
It is determined by the activity of effectors.
An increase in the heart rate when a person goes from a lying to a standing position results from _______.
negative feedback: a drop in blood pressure causes an increase in heart rate.
Which of the following statements is false regarding sweating as a homeostatic mechanism?
It is dependent on positive feedback.
An increase in plasma glucose concentration __________.
stimulates the pancreatic islets to release insulin.
A decrease in insulin secretion and an increase in glucagon secretion ________.
occurs during fasting.
What type of tissue is characterized by an abundance of extracellular material?
Connective
What type of tissue covers and lines the body surface?
Epithelial
A change from a set point is __________ in a negative feedback loop.
reversed
Which of the following hormones is released by the anterior pituitary as a part of a positive feedback loop between it and the ovary prior to ovulation?
Luteinizing hormone
Which of the following hormones, released by the corpus luteum after ovulation, creates a negative feedback effect on the hypothalamus and anterior pituitary?
Progesterone
Which of the following ovarian hormones is involved in both positive and negative feedback loops with the hypothalamus and the anterior pituitary?
Estrogen
The first step in the scientific method involves the formation of a(n) ________.
hypothesis
Phase ________ clinical trials maximize the number of test participants and include human participants of both sexes, different ethnic groups, and those who have health problems besides the one that the drug is designed to treat.
III
When blood glucose levels rise, the pancreatic islets are stimulated to release insulin, which acts on target cells to uptake glucose from the blood. Thus, the islets serve as the ________ in the feedback loop. Sensors Integrating center All of the choices are correct Effectors
All of the choices are correct
Both ________ and ________ are the regulators of effectors in most feedback loops.
hormones; nerve impulses
Homeostatic regulatory mechanisms known as ________ are "built-in" to the organs being regulated.
intrinsic
The normal range of blood glucose concentration after fasting is approximately ________.
70 to 99mg/100 ml
When a vessel is damaged, chemicals are released from the vessel walls that attract platelets to the site of the damage. As they accumulate, more chemicals that attract more platelets to the area until the bleeding stops. This represents ________ feedback, with the platelets acting as the ________.
positive; integrating center
Which types of connections allow epithelial cells to form strong membranes?
Junctional complexes
Units of bone composed of concentric rings of lamellae with trapped osteocytes are called ________.
Osteon and haversian systems
Epithelial tissues that are more than one layer thick are called ________.
stratified
Which glands are primarily responsible for thermoregulation?
Eccrine sweat glands
Which of the following is a characteristic of smooth muscle?
Found in the walls of the digestive tract
The cells that secrete fibers and matrix that create bone tissue are known as ________.
osteoblasts
Contraction of ________ muscle can be consciously controlled.
skeletal
Cartilage cells are known as ________.
chondrocytes
Which of the following is FALSE regarding the extracellular fluid compartment?
It makes up 65% of the total body water
Adult stem cells may be found in ________.
hair follicles, the brain, red bone marrow, and skeletal muscle
How does the skin protect a person from the ultraviolet rays of the sun?
Produces melanin
The zygote (fertilized egg) has the ability to produce all the various types of cells found in the body. Therefore, it is a(n) ________ cell.
totipotent
The hypodermis is primarily composed of ________.
adipose tissue
__________ is the study of biological function; how the body works
Physiology
____________ concerns how disease or injury affects physiological processes
Pathophsiology
____________ ____________ studies the differences and similarities in the functions of invertebrates and vertebrates and has aided in the development of pharmaceutical drugs
Comparative physiology
For developing pharmaceuticals, research begins by studying the effects of a chemical on cells in vitro (in a ______ _). Next, studies are done in animals to see if the same effects occur in vivo (in a _ _____) and if there are any toxic side effects.
culture dish living creature
Explain each of the phases of clinical trials
Phase I: tests the drug on healthy human volunteers to test for side effects, rates of passage (half-life, toxicity), dosage, etc. Phase II: to test its effectiveness on people with the particular disease. Phase III: conducted on a large number of people to include both sexes, many age groups and ethnicities, and people with more than one health condition. From here, the FDA can approve the drug for sale. Phase IV: tests other applications for the drug
Homeostasis is accomplished most often by ________ ____________ _______.
negative feedback loops
What are the three components of negative feedback loops?
Receptors: act as sensors in the body to detect change and send information to the
Integrating Center: which assesses change around a set point, then sends instructions to an:
Effector (muscles or glands), which can make the appropriate adjustments to encounter the change from the set-point)
Negative feedback loops moves in the ______ direction from the change and is a ___________ process.
opposite, continous
_________________ effectors help maintain homeostasis by often maintaining by opposing effectors that move conditions in opposite directions
Antagonistic
Does positive feedback work alone?
No, it doesn't, it has to work with negative feedback loops
Regulation of processes within organs can occur in two ways?
Intrinsically: cells within the organ sense a change and signal to neighboring cells to respond appropriately Extrinsically: the brain (or other organs) regulates an organ using the endocrine or nervous system
The endocrine system releases hormones ______ the blood, which transports them to the target organ
into
What are the four major categories of tissues?
muscle, nervous, epithelial, and connective tissues
Muscle tissue: What are the three types of muscles that are specialized in contraction?
Skeletal, cardiac, and smooth muscles
Muscle tissue: Skeletal Muscle is known for its ________ muscle. Also, it has visible ______ from sarcomeres.
voluntary (muscle you can consciously control)
striations
Muscle tissue: What is a syncytium? Muscle tissue can produce a _______ response
Union of separate cells called myoblasts to form myofibers (multiple nuclei in one cell)
graded (determining strength)
Muscle tissue: Which tissue is found only in the heart? Fibers are _, branched, and interconnected both physically and electrically Striated, but very _ in structure and action from skeletal muscle
Cardiac short different
Muscle tissue: Is cardiac tissue voluntary? What are the specialized cell connections that allow passage of sodium ions between cells Can cardiac tissue produce a graded contraction>
No
Intercalated discs
No
Muscle tissue: Where is smooth tissue found? Is it striated? What is the coordinated, wave-like contraction of smooth muscle layers to more substances through the organs
Found in the walls of digestive, urinary, and reproductive organs, blood vessels, and bronchioles of the lungs (hollow organs)
Not striated, and is involuntary
Peristalsis
Nerve Tissue
Where is nerve tissue found?
Composed of ________ and ___________
Found in the brain, spinal cord, and nerves
neurons, neuroglia
Nerve Tissue
Neurons conduct impulses and have three parts which are?
Neuroglia are supporting cells that do not conduct a ______ _________ but are essential for neuron function
Dendrites (short, highly branched extensions that receive signals), axon (long, single extension that sends signal, and cell body (metabolic center containing the nucleus)
nerve impulse
Epithelial tissue
Where is it found?
Are classified by the number of layers? What are the two types?
forms the membranes that cover body surfaces and line the inside of hollow organs and glands
Simple epithelium (one layer and is specialized for transport of substances)
Stratified epithelium (composed of multiple layers and provides protection)
What are the three types of shapes of epithelial tissues?
Squamous, cuboidal, and columnar
Simple squamous epithelium allows for rapid __________ as in the alveoli of the lungs. Simple cuboidal epithelium allows for ________ of substances as in various glands. Simple columnar epithelium allows for absorption as found in the wall of the _______ _____________.
diffusion, secretion, small intestine
For stratified epithelial tissue, what are held together by structures called? Explain keratinized versus nonkeratinized membranes?
Intercellular junctions (collectively known as junctional complexes). To provide protection and make sure tissue is tight.
Nonkeratinized membranes have living cells in all layers and keratinized membranes have cells filled with keratin, a water-resistant protein, and layers of dead cells on the surface
Epithelial tissue: Exocrine glands are derived from _______ tissues and secretions are transported by _______.
epithelial, ducts
Epithelial tissue: Secretory portions may be tubes or _____ groups. What are the two types of sweat glands?
Acini (clusters, rounded at the bottom)
Eccrine or merocrine (thermoregulation) and apocrine (located in axilla and pubic region)
Epithelial tissue: Do endocrine glands have ducts? Examples of endocrine glands?
No so they secrete into capillaries within the body
Thyroid glands, adrenal glands, etc.
Connective tissue is characterized by a _____ made up of protein fibers, extracellular material, and specialized cells. What are the four major categories of connective tissue?
matrix
connective tissue proper, cartilage, bone, and blood
Connective tissue proper is composed of protein fibers and a ___ - ______- ground substance. What are the four subtypes?
gel-bound
Loose: collagen fibers scattered loosely with room for blood vessels and nerves (dermis of the skin)
Dense regular: densely packed collagen fibers with little room for ground substance (tendons and ligaments)
Adipose tissue stores fat
Dense irregular connective tissue: composed of densely packed collagen fibers in various arrangements to resist forces
Cartilage connective tissue is composed of cells called ____________ surrounded by a semi-solid ground substance. Serves as a template skeleton during _____ ______________. Found in _ to provide a gliding surface for bones.
chondrocytes bone development joints
Bone: cells called ____________ trap mineral salt, forming concentric layers of calcified materials around a canal filled with blood vessels and nerves. Once the matrix has hardened, the cells are called osteocytes and live in spaced called ____________.
osteoblasts lacunae
Stem Cells What are the three embryonic germ layers? Zygotes are _, which means their cells can become any type of cell. These are true stem cells. Embryonic stem cells are _ - can form any type of unrelated cells
Endoderm, mesoderm, and ectoderm
totipotent
pluripotent
Intracellular: area inside the cells; contain _____% of total body water
65