5. Virology I - PID

The study of viruses and viral diseases.

Someone who studies viruses.

The study of viruses in animals, birds, and marine species.

Disease that can be transmitted from animals to humans

Non-living entity that contains a nucleic acid genome surrounded by a protein coat. May have other layers such as a lipid envelope.

Viruses do not have cellular ___________ like mitochondria, chloroplasts, golgi, and ER/RER.

All viruses are obligate intracellular

Viruses do not have the capacity to multiply by ________ (such as binary fision or mitosis).

The protein shell of a virus that encases the viral nucleic acid or genome.

Viral structure made up of capsomeres held together by non-covalent bonds.

= Capsid + viral nucleic acid

The potential additional layer that covers a virus capsid.

The viral envelope is usually a _______ _______ derived from the host cell.

Spiked structures on the surface of the lipid envelope.

__________ viruses have a protein capsid enclosing nucleic acid.

___________ viruses have a lipid layer enclosing the protein capsid enclosing the nucleic acid.

The ability of some viruses to alter their shape or size.

The steps of viral replication:

1. ____________

2. penetration

3. uncoating

4. synthesis of viral nucleic acid and protein

5. assembly and maturation

6. release in large numbers

The steps of viral replication:

1. attachment

2. ____________

3. uncoating

4. synthesis of viral nucleic acid and protein

5. assembly and maturation

6. release in large numbers

The steps of viral replication:

1. attachment

2. penetration

3. ____________

4. synthesis of viral nucleic acid and protein

5. assembly and maturation

6. release in large numbers

The steps of viral replication:

1. attachment

2. penetration

3. uncoating

4. ______ of viral ________ ______ and ________

5. assembly and maturation

6. release in large numbers

The steps of viral replication:

1. attachment

2. penetration

3. uncoating

4. synthesis of viral nucleic acid and protein

5. __________ ______ _________

6. release in large numbers

The steps of viral replication:

1. attachment

2. penetration

3. uncoating

4. synthesis of viral nucleic acid and protein

5. assembly and maturation

6. __________ in large numbers

Virus replication in a host cell can cause ________ _______ by lysis, alteration in the cell membrane, or apoptosis.

Virus replication in a host cell can cause ______ _________ __________ to an infected cell in the case of a latent or chronic infection.

Virus replication in a host cell can cause _________ of a cell from a normal to malignant one.

Virus replication in a host cell can cause _________, producing multinucleated cells.

ICTV stands for

Viruses may be classified based on the nature of their ___________ and ___________ diversity.

Viruses may be classified based on their _______ strategies.

Viruses may be classified based on their formation (___________).

Viruses are typically diagnosed by gross evaluation and

Viruses are typically diagnosed by histology or

Damage or morphological changes to host cells during viral invasion

Viruses can be detected by isolation or

The morphology of a virus can be identified and studied using

Detection of a viral antigen or host antibody

Detection of viral nucleic acids via molecular biology

Viruses can be treated with __________ ___________, interferon therapy, or administration of synthesized or natural antibodies.

Viruses can be treated with antiviral drugs, _________ _________, or administration of synthesized or natural antibodies.

Viruses can be treated with antiviral drugs, interferon therapy, or administration of synthesized or natural _____________.

Viral diseases can be prevented or controlled by proper hygiene and sanitation, by eliminating arthropod vectors, by quarantining and culling of sick individuals, or

Viral diseases can be prevented or controlled by vaccination, by eliminating arthropod vectors, by quarantining and culling of sick individuals, or by proper hygiene and

Viral diseases can be prevented or controlled by vaccination, by proper hygiene and sanitation, by quarantining and culling of sick individuals, or by eliminating

Viral diseases can be prevented or controlled by vaccination, proper hygiene and sanitation, eliminating arthropod vectors, or by ___________ and _________ of sick individuals.